Implication of the host TGFβ pathway in the onset of symbiosis between larvae of the coral Fungia scutaria and the dinoflagellate Symbiodinium sp. (clade C1f)
| Autor: | Jérémy Berthelier, Virginia M. Weis, Christine E. Schnitzler, Elisha M. Wood-Charlson, Angela Z. Poole, Olivier Detournay |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Innate immune system Dinoflagellate biology Host (biology) 030106 microbiology Symbiodinium Transforming growth factor beta Cnidarian biochemical phenomena metabolism and nutrition Aquatic Science biology.organism_classification Cell biology 03 medical and health sciences 030104 developmental biology Immune system Symbiosis Coral bleaching Fungia scutaria Botany biology.protein Secretion |
| Zdroj: | Coral Reefs (0722-4028) (Springer), 2017-12, Vol. 36, N. 4, P. 1263-1268 |
| ISSN: | 1432-0975 0722-4028 |
| DOI: | 10.1007/s00338-017-1621-6 |
| Popis: | Dinoflagellate-cnidarian associations form both the trophic and structural foundation of coral-reef ecosystems. Previous studies have highlighted the role of host innate immunity in regulation of these partnerships. This study reveals the presence of a transforming growth factor beta (TGF beta) in the coral Fungia scutaria that clusters with TGF beta sensu stricto (ss) from other animals. In functional studies of F. scutaria larvae, we show that (1) TGF beta ss mRNA is expressed during early stages of development prior to the onset of symbiosis; (2) apparent interference of the TGF beta pathway impairs the onset of symbiosis; and (3) this effect is associated with an increase of cytotoxic nitric oxide secretion, an immune response. This work highlights the importance of the TGF beta pathway in early life-history stages of corals by suggesting that its inhibition impacts the onset of symbiosis. |
| Databáze: | OpenAIRE |
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