Novel Rearrangements of 2,3-Dimercapto-1-propanol Derivatives: Formation of Dialkyl Sulfide, Dialkyl Disulfide, and 1,2,3-Tris(alkylthio)propane

Autor:	Chi Wi Ong, J. Wang, Yi Meen Chou
Rok vydání:	1996
Předmět:	chemistry.chemical_classification Sulfide Organic Chemistry Sulfuric acid Alkylation Medicinal chemistry Catalysis chemistry.chemical_compound 1-Propanol chemistry Propane Organic chemistry Rearrangement reaction Alkyl
Zdroj:	The Journal of organic chemistry. 61(23)
ISSN:	1520-6904
Popis:	The base alkylation of 2,3-dimercapto-1-propanol with alkyl halides leads in good yield to 2,3-bis(alkylthio)-1-propanol and dialkyl sulfide. The reaction of 2,3-bis(alkylthio)-1-propanol with catalytic concentrated sulfuric acid proceeds with rearrangement to give 1,2,3-tris(alkylthio)propane and dialkyl disulfide. The rearrangement reaction takes place through a common intermediate thiaranium intermediate 8.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b8971088aa3ab1cd1ca828863b7e00 https://pubmed.ncbi.nlm.nih.gov/11667811 Zobrazit plný text záznamu