Absence of Selection for Quantum Coherence in the Fenna–Matthews–Olson Complex: A Combined Evolutionary and Excitonic Study
| Autor: | Eugene I. Shakhnovich, Rafael G. Saer, Romain A. Studer, Alán Aspuru-Guzik, Florian Häse, Stéphanie Valleau, Christoph Kreisbeck, Robert E. Blankenship |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Photosynthetic reaction centre Physics::Biological Physics Quantitative Biology::Biomolecules 010304 chemical physics General Chemical Engineering Exciton General Chemistry Biology Photosynthesis Photosynthetic bacterium 01 natural sciences lcsh:Chemistry 03 medical and health sciences 030104 developmental biology lcsh:QD1-999 Chemical physics 0103 physical sciences Energy variation Atomic physics Quantum Fenna-Matthews-Olson complex Research Article Coherence (physics) |
| Zdroj: | ACS Central Science ACS Central Science, Vol 3, Iss 10, Pp 1086-1095 (2017) |
| ISSN: | 2374-7951 2374-7943 |
| Popis: | We present a study on the evolution of the Fenna–Matthews–Olson bacterial photosynthetic pigment–protein complex. This protein complex functions as an antenna. It transports absorbed photons—excitons—to a reaction center where photosynthetic reactions initiate. The efficiency of exciton transport is therefore fundamental for the photosynthetic bacterium’s survival. We have reconstructed an ancestor of the complex to establish whether coherence in the exciton transport was selected for or optimized over time. We have also investigated the role of optimizing free energy variation upon folding in evolution. We studied whether mutations which connect the ancestor to current day species were stabilizing or destabilizing from a thermodynamic viewpoint. From this study, we established that most of these mutations were thermodynamically neutral. Furthermore, we did not see a large change in exciton transport efficiency or coherence, and thus our results predict that exciton coherence was not specifically selected for. We reconstructed an ancestral structure for the photosynthetic Fenna−Matthews−Olson complex. We studied its evolution, exciton transport, and thermodynamics and compared to current day complexes. |
| Databáze: | OpenAIRE |
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