Effects of Lower Past-Year Serum Sodium and Hyponatremia on Depression Symptoms and Cognitive Impairments in Patients With Hemodialysis
| Autor: | Roger S. McIntyre, Lian‐Feng Lin, Michelle Iacobucci, Alexandria S. Coles, Han-Pin Hsiao, Vincent Chin-Hung Chen, Szu‐Shan Fan, Yi-Lung Chen, Chin‐Wen Hsieh, Jun-Cheng Weng, Duujian Tsai |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Renal Dialysis Internal medicine Surveys and Questionnaires medicine Humans Cognitive Dysfunction Cognitive rehabilitation therapy Renal Insufficiency Chronic Depression (differential diagnoses) Aged Retrospective Studies business.industry Depression Confounding Sodium Cognition Hematology Middle Aged medicine.disease Patient Health Questionnaire Nephrology Female Hemodialysis Hyponatremia business Kidney disease |
| Zdroj: | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis TherapyREFERENCES. 24(2) |
| ISSN: | 1744-9987 |
| Popis: | The relationship between hyponatremia, depression symptoms, and cognitive impairments in patients receiving hemodialysis treatment remain unclear. This study aimed to examine the impact of past-year average serum sodium levels on current depression symptoms and cognitive impairments in patients receiving hemodialysis, with adjustment for possible confounders. A total of 200 participants were recruited for this study. Depression symptoms and cognitive impairments were assessed using the Patient Health Questionnaire and Perceived Deficits Questionnaire-5, respectively. Additionally, sociodemographic features, physical health, metabolic factors, and substance use information were collected. Significant associations between serum sodium levels, depression symptoms, and cognitive impairments were found after multivariate regression analysis. Furthermore, such differences were observed profoundly in moderate to profound hyponatremia. Our study revealed exclusive relationships between hyponatremia, depression symptoms, and cognitive impairments. As such, programs of cognitive rehabilitation and emotional regulation should be included in the prevention of chronic kidney disease for moderate to profound hyponatremia. |
| Databáze: | OpenAIRE |
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