Excimer laser-assisted lamellar keratoplasty and the corneal endothelium
| Autor: | Maria Gabriella La Tegola, Francesco Boscia, Carlo Sborgia, Giovanni Alessio, Milena L'Abbate |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Corneal endothelium Keratoconus Materials science genetic structures Confocal medicine.medical_treatment Visual Acuity Cell Count Excimer Refraction Ocular Corneal Transplantation Young Adult Optical coherence tomography Ophthalmology Cornea medicine Humans Retrospective Studies Microscopy Confocal medicine.diagnostic_test Endothelium Corneal Ablation medicine.disease eye diseases Surgery Transplantation medicine.anatomical_structure Female Lasers Excimer sense organs Tomography Optical Coherence |
| Zdroj: | American journal of ophthalmology. 150(1) |
| ISSN: | 1879-1891 |
| Popis: | Purpose To evaluate endothelial changes after excimer laser-assisted lamellar keratoplasty. Design Retrospective, interventional case series. Methods Seven eyes of 7 keratoconus patients were evaluated for 1 year after pachymetry-guided lamellar keratoplasty, performed using the iRES Laser (Ligi Tecnologie Medicali S.p.A.), with the Corneal Lamellar Ablation for Transplantation software (Ligi Tecnologie Medicali S.p.A.) procedure. Both anterior segment optical coherence tomography (Visante OCT; Carl Zeiss Meditec, Inc) and in vivo confocal microscopy (Corneal Confocal Microscope CS4; NIDEK Technologies) images were collected. Results Changes in morphologic features were investigated and the endothelium was assessed quantitatively in all 7 patients. In 6 eyes, we measured a mean residual bed thickness of 151.3 ± 5.46 μm, and a mean endothelial cell density loss of 5.38% at 1 year after surgery, as compared with preoperative values. The mean percentage hexagonality change was 15.67%, and the mean coefficient of variation change was −21.11%. In 1 eye, a residual bed thickness of 72 μm was found and endothelial loss after 1 year was 72.26%; assessment of the coefficient of variation and percentage hexagonality by manual Confoscan4 software (NIDEK Technologies) was not practicable in this case. Conclusions Our results showed that the Corneal Lamellar Ablation for Transplantation procedure induced mild changes to the endothelium in corneas with a mean residual bed thickness of 151.3 ± 5.46 μm, but serious damage in one eye with a residual bed thickness of 72 μm. |
| Databáze: | OpenAIRE |
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