Enigma demencije Lewyjevih tjelešaca: prikaz slučaja
| Autor: | Ivona Orlović, Darko Vlahović, Dalibor Karlović, Vjekoslav Peitl, Matija Bartolović, Katarina Marušić, Ines Šiško Markoš |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Exacerbation Hallucinations Parkinsonian disorders lcsh:Medicine Disease Case Reports Lewy body disease Emission computerized tomography Pharmacotherapy Cognitive dysfunction Medicine Dementia Cholinesterase inhibitors Lewy body business.industry Demencija Lewyjevih tjelešaca Kognitivno oštećenje Halucinacije Parkinsonov sindrom Inhibitori kolinesteraze Demencija lcsh:R Cognition General Medicine medicine.disease Cholin-esterase inhibitors Presentation (obstetrics) business |
| Zdroj: | Acta Clinica Croatica Acta clinica Croatica Volume 59. Issue 4. Acta Clinica Croatica, Vol 59., Iss 4., Pp 771-775 (2020) |
| ISSN: | 0353-9466 1333-9451 |
| DOI: | 10.20471/acc.2020.59.04.27 |
| Popis: | Lewy body dementia is a progressive neurodegenerative disease and is considered to be the second most common cause of dementia in the elderly. Because of the complexity of clinical presentation, it is often misdiagnosed and mistaken for other dementias, which may result in administering inappropriate therapy, and thus worsening of the patient condition. We reviewed a case of a 71-year-old patient whose clinical presentation gradually occurred with complex visual hallucinations, atypical extrapyramidal motor symptoms, fluctuating cognitive impairments with delirious episodes, and oscillating syncope. Depressive mood, impaired daily functioning and sensitivity to antipsychotics were also noted. Extensive diagnostic workup was performed with neuropsychological testing and use of single-photon emission computerized tomography. Considering the clinical presentation and diagnostic procedures performed, the diagnosis of Lewy body dementia was set and pharmacotherapy was revised. We discuss the importance of taking overall clinical presentation and diagnostic treatment in consideration and applying appropriate therapy to slow down the progression of the disease and exacerbation of the patient’s psychological functions. Demencija Lewyjevih tjelešaca je neurodegenerativna bolest i drugi najčešći uzročnik demencije u starijih osoba. Zbog složenosti kliničke slike često se pogrešno dijagnosticira i nerijetko zamijeni s drugim demencijama, što dovodi do primjene neodgovarajuće terapije, a time i pogoršanja stanja bolesnika. Prikazujemo slučaj bolesnika u dobi od 71 godine kod kojega se klinička slika postupno prezentirala složenim vizualnim halucinacijama, atipičnim ekstrapiramidnim motoričkim ispadima, fluktuirajućim kognitivnim smetnjama uz delirantne epizode i oscilirajuće sinkope. Kod bolesnika je zabilježeno depresivno raspoloženje, narušeno svakodnevno funkcioniranje i osjetljivost na psihofarmake. Provedena je opširna dijagnostička obrada uz neuropsihologijsko testiranje i primjenu jednofotonske emisijske tomografije. Na temelju kliničke slike i diferencijalno dijagnostičke obrade posumnjalo se na demenciju Lewyjevih tjelešaca. Raspravljamo o važnosti uzimanja u obzir cjelokupne kliničke slike i dijagnostičke obrade te primjeni odgovarajućeg liječenja u svrhu prevencije progresije bolesti i pogoršanja psihičkih funkcija bolesnika. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|