A Case Study in Model Failure? COVID-19 Daily Deaths and ICU Bed Utilisation Predictions in New York State

Autor: Vincent W. L. Chin, Martin A. Tanner, John P. A. Ioannidis, Noelle I. Samia, Ori Rosen, Sally Cripps, Roman Marchant
Rok vydání: 2020
Předmět:
medicine.medical_specialty
Physics - Physics and Society
Coronavirus disease 2019 (COVID-19)
Epidemiology
Computer science
Pneumonia
Viral

New York
FOS: Physical sciences
Physics and Society (physics.soc-ph)
030204 cardiovascular system & hematology
03 medical and health sciences
Betacoronavirus
0302 clinical medicine
Statistics
medicine
Humans
030212 general & internal medicine
Point estimation
Mortality
Quantitative Biology - Populations and Evolution
Model evaluation
Pandemics
Uncertainty quantification
Bed Occupancy
Ground truth
Models
Statistical

SARS-CoV-2
Public health
Hospital resource utilisation
Populations and Evolution (q-bio.PE)
COVID-19
Coronavirus
Intensive Care Units
Trustworthiness
FOS: Biological sciences
State (computer science)
Public Health
Coronavirus Infections
Forecasting
Zdroj: European Journal of Epidemiology
DOI: 10.48550/arxiv.2006.15997
Popis: Forecasting models have been influential in shaping decision-making in the COVID-19 pandemic. However, there is concern that their predictions may have been misleading. Here, we dissect the predictions made by four models for the daily COVID-19 death counts between March 25 and June 5 in New York state, as well as the predictions of ICU bed utilisation made by the influential IHME model. We evaluated the accuracy of the point estimates and the accuracy of the uncertainty estimates of the model predictions. First, we compared the “ground truth” data sources on daily deaths against which these models were trained. Three different data sources were used by these models, and these had substantial differences in recorded daily death counts. Two additional data sources that we examined also provided different death counts per day. For accuracy of prediction, all models fared very poorly. Only 10.2% of the predictions fell within 10% of their training ground truth, irrespective of distance into the future. For accurate assessment of uncertainty, only one model matched relatively well the nominal 95% coverage, but that model did not start predictions until April 16, thus had no impact on early, major decisions. For ICU bed utilisation, the IHME model was highly inaccurate; the point estimates only started to match ground truth after the pandemic wave had started to wane. We conclude that trustworthy models require trustworthy input data to be trained upon. Moreover, models need to be subjected to prespecified real time performance tests, before their results are provided to policy makers and public health officials.
Databáze: OpenAIRE