Bilateral pleural metastases of a primary central nervous system neuroblastoma in an adult: First case in the world

Autor: R. Kaddoussi, Ahlem Bellalah, Saoussen Cheikh Mhamed, Asma Migaou, Samah Joobeur, Mabrouk Abdelaaly, Ahmed Ben Saad, Nesrine Fahem, Lobna Loued, Naceur Rouatbi
Rok vydání: 2021
Předmět:
Zdroj: Respirology Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Respirology Case Reports
ISSN: 2051-3380
Popis: Primary central nervous system neuroblastoma (PCNS‐NBL) is a rare and aggressive malignant tumour. Pleural metastases of PCNS‐NBL have not been documented before. We report a case of a 30‐year‐old male patient, with a history of PCNS‐NBL treated with surgery, radiation and chemotherapy. Three years later, he presented an aggravated dyspnoea with impaired general condition. The different investigations confirmed that his PCNS‐NBL has relapsed with bone, lymph nodes and bilateral pleural metastases. Because of the disseminated disease and the poor general condition of the patient, only symptomatic treatment measures were preconized. The patient died 3 months later following cardiorespiratory arrest. To the best of our knowledge, this is the first case reporting bilateral pleural metastases of a PCNS‐NBL in a young adult.
This study presents an unusual case of bilateral pleural metastases of a primary cerebral tumour. The metastases were confirmed through pathology. Pleural secondary location was never described before.
Databáze: OpenAIRE