Schwannian Crystalline-like Inclusions Bodies (Fardeau-Engel Bodies) Revisited in Peripheral Neuropathies
| Autor: | Claude Vital, Sandrine Bouillot, Anne Vital, Marie-Hélène Canron |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Schwann cell Biology Mitochondrion Nerve Fibers Myelinated Pathology and Forensic Medicine Double membrane Schwann cell cytoplasm Structural Biology Organelle medicine Humans In patient Child Aged Aged 80 and over Inclusion Bodies Mitochondrial Myopathies Peripheral Nervous System Diseases Peroneal Nerve Middle Aged medicine.disease Axons Mitochondria Muscle Peripheral Peripheral neuropathy medicine.anatomical_structure Female Schwann Cells Crystallization |
| Zdroj: | Ultrastructural Pathology. 26:9-13 |
| ISSN: | 1521-0758 0191-3123 |
| DOI: | 10.1080/01913120252934279 |
| Popis: | In 1969, Fardeau and Engel described polygonal organelles containing crystalline-like structures located in the Schwann cell cytoplasm of unmyelinated fibers. Such inclusions were reported in various conditions, mainly with axonal lesions. They were also reported in a few cases of peripheral neuropathy associated with primary mitochondriopathy. Although they are surrounded by a double membrane, their mitochondrial origin is not definitely proven. Their significance remains obscure but they deserve to be better known as Fardeau-Engel bodies, so as not to be mistaken with mitochondrial crystalline inclusions, which are frequently observed in patients with ragged-red fibers in muscle. |
| Databáze: | OpenAIRE |
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