Neuropsychological dysfunction in children with chronic low-level lead absorption
| Autor: | NormanW Staehling, RobertW. Baloh, RandolphH. Whitworth, BernardF Rosenblum, WilliamF Barthel, Philip J. Landrigan |
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| Rok vydání: | 1975 |
| Předmět: |
Pediatrics
medicine.medical_specialty Adolescent Colic Mental ability Lead absorption Hyperkinesis Absorption Neurologic Manifestations Perceptual Disorders Seizures Medicine Humans Affective Symptoms Child Neurologic Examination business.industry Neuropsychology Age Factors Wechsler Scales General Medicine Environmental Exposure Texas Lead Poisoning Lead Socioeconomic Factors Motor Skills Child Preschool Pica Nervous System Diseases business Cognition Disorders |
| Zdroj: | Lancet (London, England). 1(7909) |
| ISSN: | 0140-6736 |
| Popis: | To investigate the relation between low-level absorption and neuropsychological function, blind evaluations were under-taken in forty-six symptom-free children aged 3-15 years with blood-lead concentrations of 40-68 mug. per 100 ml. (mean 48 mug. per 100 ml.) and in seventy-eight ethnically and socioeconomically similar controls with levels greater than mug. per 100 ml. (mean 27 mug. per (100 ml). All children lived within 6-6 km. of a large, lead-emitting smelter, and in many cases residence there had been lifelong. Mean age in the lead group was 8-3 years and in the controls 9-3. Testing with Wechsler intelligence scales for schoolchildren and preschool children (W.I.S.C. and W.P.P.S.I.) showed age-adjusted performance I.Q. to be significantly decreased in the group with higher lead levels (mean scores, W.I.S.C. plus W.P.P.S.I., 95 v. 103). Children in all ages in the lead group also had significant slowing in a finger-wrist tapping test. Full-scale I.Q., verbal I.Q., BEHAVIOUR, AND HYPERACTIVITY RATINGS DID NOT DIFFER. |
| Databáze: | OpenAIRE |
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