The tortoiseshell pattern in one or both sides of the submandibular glands in mucosa-associated lymphoid tissue lymphoma is related to chromosomal aberrations and the disease extent
| Autor: | Guilan Jin, Hayato Miyachi, Yoko Ogase, Yoshihide Ohta, Satomi Asai, Kenji Okami, Yoshiaki Ogawa, Hiromichi Matsushita, Naoya Nakamura |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Pathology medicine.medical_specialty Mucosa-Associated Lymphoid Tissue Lymphoma Disease Sensitivity and Specificity Lesion stomatognathic system medicine Humans Radiology Nuclear Medicine and imaging Genetic Predisposition to Disease B cell Aged Ultrasonography Chromosome Aberrations Radiological and Ultrasound Technology business.industry MALT lymphoma Anatomy Lymphoma B-Cell Marginal Zone Middle Aged medicine.disease Lymphoma Submandibular Gland Neoplasms medicine.anatomical_structure Lymphatic system visual_art visual_art.visual_art_medium Female Tortoiseshell medicine.symptom business |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 29(1) |
| ISSN: | 1550-9613 |
| Popis: | Objective Lesions of mucosa-associated lymphoid tissue (MALT) lymphoma in the submandibular glands are localized or a part of systemic involvement in association with chromosomal aberrations. This series was undertaken to investigate the sonographic features of MALT lymphoma in the submandibular glands and their relationships with chromosomal aberrations and the disease extent. Methods A total of 5 patients with MALT lymphoma without Sjogren syndrome in the submandibular glands were enrolled in this series. Patients underwent sonography of the submandibular glands with a high-resolution transducer before surgical biopsy of the main lesion. Sonographic characteristics of the lesions were described for their location, presence of a posterior echo, texture, and presence of an internal echo. Results Sonography in all cases showed hypoechoic and solid masses with increased posterior echo enhancement. There was an arrangement of hypoechoic small compartments demarcated by hyperechoic contour lines, which had a tortoiseshell pattern. This pattern was classified into 2 types according to its location: a lesion in the right or left side and lesions in both sides of the submandibular glands, found in 3 and 2 patients, respectively. The latter 2 cases had chromosomal aberrations of t(11;18)(q23;q23) and t(12;18)(q22;q21), respectively, and were revealed as secondary organ involvement. Conclusions The sonographic appearance of MALT lymphoma in the submandibular glands was characterized by the tortoiseshell pattern in both primary and secondary lesions. Detection of this pattern in both sides of the submandibular glands can be an indicator of chromosomal aberrations and systematic involvement of the disease. |
| Databáze: | OpenAIRE |
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