Epithelial-Myoepithelial Carcinoma of the Minor Salivary Glands: Case Series with Comprehensive Review

Autor: Yasuyuki Michi, Hirofumi Tomioka, Hideaki Hirai, Kou Kayamori, Tohru Ikeda, Misaki Yokokawa, Yuko Yamagata, Yuriko Sato, Hiroyuki Harada, Takeshi Kuroshima, Kohei Okuyama, Yoshihisa Kashima, Maiko Tsuchiya
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Diagnostics
Diagnostics, Vol 11, Iss 2124, p 2124 (2021)
ISSN: 2075-4418
Popis: Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland tumor that is histologically characterized by biphasic tubular structures composed of inner ductal and outer clear myoepithelial cells, which is especially uncommon in the minor salivary glands (MSG). Because of its histologic variety, complexity, and heterogeneity, it is sometimes challenging to make the accurate diagnosis. Here, we report a literature review of EMC of the MSGs with our experience of two cases. Incisional biopsy was suggestive of pleomorphic adenoma in Case 1 and pleomorphic adenoma or a low-grade salivary gland carcinoma in Case 2. Both cases were performed intraoral tumor resection, and they have good postoperative courses and are alive with no evidence of local recurrence or metastasis at 31 and 16 months, respectively. Considering that the anatomy, structure, and size of salivary glands are quite different from MSGs, it might be difficult to predict EMCs of the MSG similarly to EMCs of the major salivary glands. This comprehensive review also reports the features of EMC of the MSG cases and the trends of diagnosis and discusses treatment strategy.
Databáze: OpenAIRE
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