Development of of macrophage migration inhibition in rabbits infected with virulent Treponema pallidum
| Autor: | James D. Folds, Joel B. Baseman, C S Pavia |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Male
Microgram Biovar Immunology Dose-Response Relationship Immunologic Virulence urologic and male genital diseases Microbiology Immunity Animals Syphilis Treponema pallidum Macrophage Migration-Inhibitory Factors Antigens Bacterial Treponema biology Macrophages Cell Migration Inhibition biology.organism_classification Virology Infectious Diseases Macrophage migration inhibition Parasitology Macrophage migration inhibitory factor Rabbits Research Article |
| Zdroj: | Infection and Immunity. 17:651-654 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.17.3.651-654.1977 |
| Popis: | Peritoneal exudate cells from rabbits infected with Treponema pallidum Nichols were used as indicators of macrophage migration inhibitory factor activity. Between 3 and 15 weeks after infection, the migration of peritoneal exudate cells was inhibited in the presence of 3 to 25 microgram of T. phagedenis biovar Reiter protein per ml. Before this period, the migration patterns of peritoneal exudate cells from infected animals were uninhibited and similar to those from noninfected control rabbits. These observations were correlated with the development of active cell-mediated immunity during experimental T. pallidum infection. |
| Databáze: | OpenAIRE |
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