Trichostemonoate, a new anticancer tirucallane from the stem bark of Walsura trichostemon
| Autor: | Kiettipum Phontree, Pongpun Siripong, Jirapast Sichaem, Santi Tip-pyang, Suttira Khumkratok |
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| Předmět: |
Pharmacology
Stem bark Meliaceae Traditional medicine biology Molecular Structure Chemistry Plant Extracts Plant Science General Medicine biology.organism_classification Antineoplastic Agents Phytogenic Triterpenes Complementary and alternative medicine Cell Line Tumor Drug Discovery Walsura Plant Bark Humans |
| Zdroj: | Scopus-Elsevier |
| Popis: | Trichostemonoate (1), a new tirucallane, together with four known compounds, 11α,20-dihydroxydammar-24-ene-3-one (2), sapelin E acetate (3), grandifolinolenenone (4) and α-mangostin (5), were isolated from the stem bark of Walsura trichostemon. The structural assignment of the new compound was based on spectroscopic methods. All isolated compounds were evaluated for their cytotoxicity against five cancer cell lines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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