Bayesian Quantitative Electrophysiology and Its Multiple Applications in Bioengineering
Autor: | Loren W. Nolte, Roger C. Barr, Andrew E. Pollard |
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Rok vydání: | 2010 |
Předmět: |
Computer science
Bayesian probability Biomedical Engineering Electrophysiological Phenomena Machine learning computer.software_genre Bayesian inference Article Domain (software engineering) Bayes' theorem Humans Vision Ocular Models Statistical Interpretation (logic) business.industry Mathematical statistics Multiple applications Brain Bayes Theorem Genomics Models Theoretical ROC Curve Artificial intelligence business computer |
Zdroj: | IEEE Reviews in Biomedical Engineering. 3:155-168 |
ISSN: | 1941-1189 1937-3333 |
Popis: | Bayesian interpretation of observations began in the early 1700s, and scientific electrophysiology began in the late 1700s. For two centuries these two fields developed mostly separately. In part that was because quantitative Bayesian interpretation, in principle a powerful method of relating measurements to their underlying sources, often required too many steps to be feasible with hand calculation in real applications. As computer power became widespread in the later 1900s, Bayesian models and interpretation moved rapidly but unevenly from the domain of mathematical statistics into applications. Use of Bayesian models now is growing rapidly in electrophysiology. Bayesian models are well suited to the electrophysiological environment, allowing a direct and natural way to express what is known (and unknown) and to evaluate which one of many alternatives is most likely the source of the observations, and the closely related receiver operating characteristic (ROC) curve is a powerful tool in making decisions. Yet, in general, many people would ask what such models are for, in electrophysiology, and what particular advantages such models provide. So to examine this question in particular, this review identifies a number of electrophysiological papers in bio-engineering arising from questions in several organ systems to see where Bayesian electrophysiological models or ROC curves were important to the results that were achieved. |
Databáze: | OpenAIRE |
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