Solid-phase organic synthesis of vinyl-substituted 1,2,4-trizoles based on polymer-supported α-selenopropionic acid
Autor: | Xue-Chun Mao, Ming-Zhong Cai, Shi-Yang Fei, Shou-Ri Sheng, Lei Guo, Gui-Yun Fu |
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Rok vydání: | 2008 |
Předmět: | |
Zdroj: | ARKIVOC, Vol 2008, Iss 2, Pp 287-293 (2008) |
ISSN: | 1551-7012 |
DOI: | 10.3998/ark.5550190.0009.230 |
Popis: | Acylation of polystyrene-supported α-selenopropionic acid with acid hydrazides, followed by cyclocondensation with arylphosphazoanilides, and oxidation-elimination with 30 % hydrogen peroxide efficiently afforded vinyl-substituted 1,2,4-triazoles in good yield and purity, with advantages of decreased volatility and simplification of work-up procedure. |
Databáze: | OpenAIRE |
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