Solid-phase organic synthesis of vinyl-substituted 1,2,4-trizoles based on polymer-supported α-selenopropionic acid

Autor: Xue-Chun Mao, Ming-Zhong Cai, Shi-Yang Fei, Shou-Ri Sheng, Lei Guo, Gui-Yun Fu
Rok vydání: 2008
Předmět:
Zdroj: ARKIVOC, Vol 2008, Iss 2, Pp 287-293 (2008)
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0009.230
Popis: Acylation of polystyrene-supported α-selenopropionic acid with acid hydrazides, followed by cyclocondensation with arylphosphazoanilides, and oxidation-elimination with 30 % hydrogen peroxide efficiently afforded vinyl-substituted 1,2,4-triazoles in good yield and purity, with advantages of decreased volatility and simplification of work-up procedure.
Databáze: OpenAIRE