Genetic Counseling and Long-Term Surveillance Using a Multidisciplinary Approach in von Hippel–Lindau Disease
| Autor: | Sun Joo Yoon, Won Kyung Kwon, Geehay Hong, Ja-Hyun Jang, Byong Chang Jeong, Jae Hyeon Kim, Jong-Won Kim |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Annals of Laboratory Medicine. 42:352-357 |
| ISSN: | 2234-3814 2234-3806 |
| DOI: | 10.3343/alm.2022.42.3.352 |
| Popis: | von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by variants of the VHL tumor suppressor gene (The VHL clinic was organized at the Samsung Medical Center in 2011 and consisted of a multidisciplinary team, including an endocrinologist, urologist, general surgeon, neurosurgeon, ophthalmologist, otolaryngologist, and radiologist. Biochemical and imaging surveillance and personalized genetic counseling were conducted at the VHL clinic and patients were referred to the necessary departments upon detection of disease manifestation. We divided the patients in three groups (I-III) based on their compliance to VHL clinic attendance.Between 2011 and 2018, 50 VHL patients were identified byWe present the results of using a multidisciplinary team approach and showed that the VHL clinic strategy is useful for the comprehensive surveillance and management of VHL disease. We hope that VHL clinics will be widely set up in hospitals to improve prognosis in patients with VHL. |
| Databáze: | OpenAIRE |
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