The Concept of an Epilepsy Brain Bank
| Autor: | Jose F. Tellez-Zenteno, Adam Wu, Roland N. Auer, Richard J. Huntsman, Mirna Vrbancic, Farzad Moien-Afshari, Lizbeth Hernández-Ronquillo, Marla J. S. Mickleborough, Hajar Miranzadeh Mahabadi, Ron Borowsky, Changiz Taghibiglou, Viktor Zherebitskiy, Francisco S. Cayabyab, Alexandra Carter |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Brain tissue Review lcsh:RC346-429 03 medical and health sciences Epilepsy 0302 clinical medicine medicine brain bank Epilepsy surgery neurodegenerative diseases human Intensive care medicine Neuropharmacology lcsh:Neurology. Diseases of the nervous system business.industry Human brain clinical characterization medicine.disease Paraffin embedded 030104 developmental biology medicine.anatomical_structure Neurology Molecular mechanism epilepsy surgery epilepsy Brain bank Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Frontiers in Neurology Frontiers in Neurology, Vol 11 (2020) |
| ISSN: | 1664-2295 |
| Popis: | Epilepsy comprises more than 40 clinical syndromes affecting millions of patients and families worldwide. To decode the molecular and pathological framework of epilepsy researchers, need reliable human epilepsy and control brain samples. Brain bank organizations collecting and supplying well-documented clinically and pathophysiologically tissue specimens are important for high-quality neurophysiology and neuropharmacology studies for epilepsy and other neurological diseases. New development in molecular mechanism and new treatment methods for neurological disorders have evoked increased demands for human brain tissue. An epilepsy brain bank is a storage source for both the frozen samples as well as the formaldehyde fixed paraffin embedded (FFPE) tissue from epilepsy surgery resections. In 2014, the University of Saskatchewan have started collecting human epilepsy brain tissues for the first time in Canada. This review highlights the necessity and importance of Epilepsy Brain bank that provides unique access for research to valuable source of brain tissue and blood samples from epilepsy patients. |
| Databáze: | OpenAIRE |
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