Have Preferences of Girls Changed Almost 3 Years after the Much Debated Start of the HPV Vaccination Program in the Netherlands? A Discrete Choice Experiment

Autor: Ida J. Korfage, Esther W. de Bekker-Grob, Harry J. de Koning, Jan Hendrik Richardus, Robine Hofman, Marjolein van Ballegooijen
Přispěvatelé: Public Health
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Pediatrics
Health Knowledge
Attitudes
Practice

Gynecologic Infections
lcsh:Medicine
Uterine Cervical Neoplasms
Discrete choice experiment
Alphapapillomavirus
Choice Behavior
Risk Factors
Surveys and Questionnaires
Medicine and Health Sciences
Public and Occupational Health
lcsh:Science
Child
Netherlands
Response rate (survey)
Cervical cancer
Multidisciplinary
Vaccination
Age Factors
Hpv vaccination
Obstetrics and Gynecology
Vaccination and Immunization
Latent class model
Infectious Diseases
Oncology
Physical Sciences
Female
Cancer Prevention
Research Article
medicine.medical_specialty
Infectious Disease Control
Adolescent
Immunology
Sexually Transmitted Diseases
Gynecologic Diseases
Drug Administration Schedule
Health Economics
SDG 3 - Good Health and Well-being
Adolescent Medicine
medicine
Humans
Papillomavirus Vaccines
Human papillomavirus
Health Care Policy
business.industry
Discrete Mathematics
Immunization Programs
lcsh:R
Papillomavirus Infections
Biology and Life Sciences
medicine.disease
Educational attainment
Health Care
Women's Health
lcsh:Q
Preventive Medicine
business
Mathematics
Zdroj: PLoS ONE
PLoS ONE, Vol 9, Iss 8, p e104772 (2014)
PLoS One (print), 9(8). Public Library of Science
ISSN: 1932-6203
Popis: Objectives: To assess how girls' preferences have changed almost 3 years after the much debated start of the human papillomavirus (HPV) vaccination program. Methods: A discrete choice experiment (DCE) was conducted among girls aged 11-15 years who were invited, or were not yet invited, to get vaccinated. A panel latent class model was used to determine girls' preferences for vaccination based on five characteristics: degree of protection against cervical cancer; duration of protection; risk of mild side-effects; age of vaccination; and the number of required doses of the vaccine. Results: The response rate was 85% (500/592). Most girls preferred vaccination at age 14 years (instead of at age 9 years) and a 2-dose scheme (instead of the current 3-dose scheme). Girls were willing to trade-off 7% (CI: 3.2% to 10.8%) of the degree of protection to have 10% less risk of mild side-effects, and 4% (CI: 1.2% to 5.9%) to receive 2 doses instead of 3 doses. Latent class analyses showed that there was preference heterogeneity among girls, i.e., higher educated girls and HPV vaccinated girls had a higher probability to opt for HPV vaccination at a higher age than lower educated girls or non-vaccinated girls. Conclusions: Three years after the start of HPV vaccination program the risk of mild side-effects and age at vaccination seem to have become less important. For the Dutch national immunization program, we recommend not to lower the current target age of 12 years. A 2-dose scheme may result in a higher uptake and we recommend that if this scheme is introduced, it needs to receive adequate publicity.
Databáze: OpenAIRE