Have Preferences of Girls Changed Almost 3 Years after the Much Debated Start of the HPV Vaccination Program in the Netherlands? A Discrete Choice Experiment
Autor: | Ida J. Korfage, Esther W. de Bekker-Grob, Harry J. de Koning, Jan Hendrik Richardus, Robine Hofman, Marjolein van Ballegooijen |
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Přispěvatelé: | Public Health |
Jazyk: | angličtina |
Rok vydání: | 2014 |
Předmět: |
Pediatrics
Health Knowledge Attitudes Practice Gynecologic Infections lcsh:Medicine Uterine Cervical Neoplasms Discrete choice experiment Alphapapillomavirus Choice Behavior Risk Factors Surveys and Questionnaires Medicine and Health Sciences Public and Occupational Health lcsh:Science Child Netherlands Response rate (survey) Cervical cancer Multidisciplinary Vaccination Age Factors Hpv vaccination Obstetrics and Gynecology Vaccination and Immunization Latent class model Infectious Diseases Oncology Physical Sciences Female Cancer Prevention Research Article medicine.medical_specialty Infectious Disease Control Adolescent Immunology Sexually Transmitted Diseases Gynecologic Diseases Drug Administration Schedule Health Economics SDG 3 - Good Health and Well-being Adolescent Medicine medicine Humans Papillomavirus Vaccines Human papillomavirus Health Care Policy business.industry Discrete Mathematics Immunization Programs lcsh:R Papillomavirus Infections Biology and Life Sciences medicine.disease Educational attainment Health Care Women's Health lcsh:Q Preventive Medicine business Mathematics |
Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 8, p e104772 (2014) PLoS One (print), 9(8). Public Library of Science |
ISSN: | 1932-6203 |
Popis: | Objectives: To assess how girls' preferences have changed almost 3 years after the much debated start of the human papillomavirus (HPV) vaccination program. Methods: A discrete choice experiment (DCE) was conducted among girls aged 11-15 years who were invited, or were not yet invited, to get vaccinated. A panel latent class model was used to determine girls' preferences for vaccination based on five characteristics: degree of protection against cervical cancer; duration of protection; risk of mild side-effects; age of vaccination; and the number of required doses of the vaccine. Results: The response rate was 85% (500/592). Most girls preferred vaccination at age 14 years (instead of at age 9 years) and a 2-dose scheme (instead of the current 3-dose scheme). Girls were willing to trade-off 7% (CI: 3.2% to 10.8%) of the degree of protection to have 10% less risk of mild side-effects, and 4% (CI: 1.2% to 5.9%) to receive 2 doses instead of 3 doses. Latent class analyses showed that there was preference heterogeneity among girls, i.e., higher educated girls and HPV vaccinated girls had a higher probability to opt for HPV vaccination at a higher age than lower educated girls or non-vaccinated girls. Conclusions: Three years after the start of HPV vaccination program the risk of mild side-effects and age at vaccination seem to have become less important. For the Dutch national immunization program, we recommend not to lower the current target age of 12 years. A 2-dose scheme may result in a higher uptake and we recommend that if this scheme is introduced, it needs to receive adequate publicity. |
Databáze: | OpenAIRE |
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