Ischemic Stroke Due to Heparin-induced Thrombocytopenia during Severe COVID-19 Infection
Autor: | Yasutaka Murakami, Shuhei Okazaki, Makoto Yamamoto, Rei Sakurai, Jyunki Jinno, Tatsuhiko Ozono, Kensuke Ikenaka, Yasufumi Gon, Kenichi Todo, Tsutomu Sasaki, Haruhiko Hirata, Akinori Uchiyama, Hideki Mochizuki |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Internal Medicine. 61:2797-2801 |
ISSN: | 1349-7235 0918-2918 |
Popis: | A 53-year-old woman with severe coronavirus disease 2019 (COVID-19) pneumonia was admitted and treated with intravenous unfractionated heparin for thromboprophylaxis under general anesthesia with mechanical ventilation. She developed right hemiparesis after hospitalization due to a large hemorrhagic infarction. Her platelet count decreased from 243,000/μL at administration to 121,000/μL. Anti-platelet factor 4-heparin antibody testing was positive according to a latex immunoturbidimetric assay. She was therefore diagnosed with heparin-induced thrombocytopenia. We immediately stopped the heparin and started argatroban; the platelet count recovered, and thrombosis did not relapse. Physicians should consider heparin-induced thrombocytopenia as a cause of ischemic stroke in patients with COVID-19 infection. |
Databáze: | OpenAIRE |
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