One-visit versus two-visit root canal treatment: effectiveness in the removal of endotoxins and cultivable bacteria
Autor: | Frederico Canato Martinho, Cláudio Antonio Talge Carvalho, Antonio Olavo Cardoso Jorge, Ana Claudia Carvalho Xavier, Adriana Chung, Marcia Carneiro Valera, Luciane Dias de Oliveira |
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Rok vydání: | 2012 |
Předmět: |
Veterinary medicine
Sodium Hypochlorite Root canal Bacterial counts Cultivable bacteria Microbiology Clinical study Calcium Hydroxide Appointments and Schedules medicine Humans General Dentistry Limulus Test Bacteriological Techniques biology Bacteria Root Canal Irrigants Chlorhexidine biology.organism_classification Bacterial Load Root Canal Therapy Endotoxins medicine.anatomical_structure Treatment Outcome Chromogenic Compounds Anti-Infective Agents Local Dental Pulp Cavity Root Canal Preparation medicine.drug |
Zdroj: | Journal of endodontics. 39(8) |
ISSN: | 1878-3554 |
Popis: | This clinical study was conducted to compare the effectiveness of 1-visit versus 2-visit root canal treatment in removing endotoxins and cultivable bacteria from primarily infected root canals.Forty-eight primarily infected root canals were selected and randomly divided into 4 groups: G1, 1% NaOCl; G2, 2% chlorhexidine (CHX) gel; G3, 1% NaOCl + Ca(OH)2; and G4, 2% CHX gel + Ca(OH)2 (all, n = 12). G1 and G2 involved 1-visit treatment, whereas G3 and G4 involved 2-visit treatment with the placement of Ca(OH)2 medication for 14 days. Samples were collected before and after root canal procedures. A chromogenic LAL assay test was used to quantify endotoxins. Culture techniques were used to determine bacterial counts.Endotoxins and cultivable bacteria were detected in 100% of the initial samples. All treatment protocols were effective in reducing bacterial load from infected root canals: G1 (1% NaOCl, 99.97%), G2 (2% CHX gel, 99.75%), G3 (1% NaOCl + Ca(OH)2, 99.90%), and G4 (2% CHX gel + Ca(OH)2, 96.81%), respectively (P.05). No differences were found in bacterial load reduction when comparing 1-visit and 2-visit treatment groups, irrespective of the irrigant tested (P.05). Higher median percentage values of endotoxin reduction were achieved in the 2-visit treatment groups (G3, 98.01% and G4, 96.81%) compared with 1-visit treatment groups (G1, 86.33% and G2, 84.77%) (all P.05).Both 1-visit and 2-visit root canal treatment protocols were effective in reducing bacteria and endotoxins, but they were not able to eliminate them in all root canals analyzed. Furthermore, 2-visit root canal treatment protocols were more effective in reducing endotoxins than 1-visit root canal treatment protocols. |
Databáze: | OpenAIRE |
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