Parametric Imaging of Biologic Activity of Atherosclerosis Using Dynamic Whole-Body Positron Emission Tomography

Autor: Thorsten Derlin, Rudolf A. Werner, Desiree Weiberg, Katja Derlin, Frank M. Bengel
Rok vydání: 2022
Předmět:
Zdroj: JACC: Cardiovascular Imaging. 15:2098-2108
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2022.05.008
Popis: For molecular imaging of atherosclerotic vessel wall activity, tracer kinetic analysis may yield improved contrast versus blood, more robust quantitative parameters, and more reliable characterization of systems biology.The authors introduce a novel dynamic whole-body positron emission tomography (PET) protocol that is enabled by rapid continuous camera table motion, followed by reconstruction of parametric data sets using voxel-based Patlak graphical analysis.Twenty-five subjects were prospectively enrolled and underwent dynamic PET up to 90 minutes after injection of 2-[Parametric MRAbsolute quantification of MR
Databáze: OpenAIRE