Flow Chemistry on Multigram Scale: Continuous Synthesis of Boronic Acids within 1 s
| Autor: | Andreas Hafner, Joerg Sedelmeier, Mark Meisenbach |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
010405 organic chemistry
Chemistry Metalation Continuous flow business.industry Scale (chemistry) Organic Chemistry Flow chemistry 010402 general chemistry 01 natural sciences Biochemistry Chemical synthesis Combinatorial chemistry 0104 chemical sciences Physical and Theoretical Chemistry Process engineering business Throughput (business) |
| Zdroj: | Organic Letters. 18:3630-3633 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.6b01681 |
| Popis: | The benefits and limitations of a simple continuous flow setup for handling and performing of organolithium chemistry on the multigram scale is described. The developed metalation platform embodies a valuable complement to existing methodologies, as it combines the benefits of Flash Chemistry (chemical synthesis on a time scale of |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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