Congenital unilateral renal tubular dysgenesis and severe neonatal hypertension
| Autor: | Robert H. Farnsworth, Sean E. Kennedy, Danielle Delaney, Vivienne Tobias |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Nephrology
medicine.medical_specialty medicine.medical_treatment Renal artery stenosis Nephrectomy Magnetic resonance angiography Diagnosis Differential Kidney Tubules Proximal Dysgenesis Internal medicine medicine Humans Heart Failure medicine.diagnostic_test business.industry Infant Newborn Captopril medicine.disease Treatment Outcome Pediatrics Perinatology and Child Health Hypertension Cardiology Female Radiology business Perfusion medicine.drug Renal tubular dysgenesis |
| Zdroj: | Pediatric nephrology (Berlin, Germany). 24(4) |
| ISSN: | 0931-041X |
| Popis: | Severe arterial hypertension rarely occurs in the neonatal period but may have life-threatening consequences. It is most often caused by renal parenchymal or vascular abnormality, which, to be accurately diagnosed, may require a combination of imaging modalities. We report on a case of neonatal hypertension presenting as cardiac failure. Initial imaging suggested unilateral renal artery stenosis, but this was not corroborated by magnetic resonance angiography. Surgical nephrectomy was curative for the hypertension and also allowed diagnosis of renal tubular dysgenesis. Unilateral congenital tubular dysgenesis without renal infarction has not been previously reported. We speculate that the condition was secondary to a period of localised hypoperfusion during early foetal life. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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