Erosive Esophagitis and Symptoms of Gastroesophageal Reflux Disease in Patients with Morbid Obesity with and without Type 2 Diabetes: a Cross-sectional Study
| Autor: | Tor-Ivar Karlsen, Dag Hofsø, Rune Sandbu, Asle W. Medhus, Marius Svanevik, Jøran Hjelmesæth, Ronette L. Kolotkin, Jolanta Lorentzen, Birgitte Seip, Heidi Borgeraas, Daniel Sifrim, Jens Kristoffer Hertel |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system diseases Cross-sectional study Endocrinology Diabetes and Metabolism Population 030209 endocrinology & metabolism Type 2 diabetes Asymptomatic Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans education education.field_of_study Nutrition and Dietetics Norway business.industry Reflux nutritional and metabolic diseases Heartburn Middle Aged medicine.disease digestive system diseases Obesity Morbid Cross-Sectional Studies Diabetes Mellitus Type 2 Gastroesophageal Reflux GERD Female 030211 gastroenterology & hepatology Surgery medicine.symptom business Esophagitis |
| Zdroj: | Obesity Surgery. 30:2667-2675 |
| ISSN: | 1708-0428 0960-8923 |
| DOI: | 10.1007/s11695-020-04545-w |
| Popis: | Type 2 diabetes (T2DM) is associated with gastroesophageal reflux disease (GERD) in the general population, but the relationship between these conditions in candidates for bariatric surgery is uncertain. We compared the prevalence of GERD and the association between GERD symptoms and esophagitis among bariatric candidates with and without T2DM. Cross-sectional study of baseline data from the Oseberg study in Norway. Both groups underwent gastroduodenoscopy and completed validated questionnaires: Gastrointestinal Symptom Rating Scale and Gastroesophageal Reflux Disease Questionnaire. Participants with T2DM underwent 24-h pH-metry. A total of 124 patients with T2DM, 81 women, mean (SD) age 48.6 (9.4) years and BMI 42.3 (5.5) kg/m2, and 64 patients without T2DM, 46 women, age 43.0 (11.0) years and BMI 43.0 (5.0) kg/m2, were included. The proportions of patients reporting GERD-symptoms were low ( |
| Databáze: | OpenAIRE |
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