A prospective multicentre screening study on multidrug-resistant organisms in intensive care units in the Dutch-German cross-border region, 2017 to 2018: the importance of healthcare structures
| Autor: | Corinna Glasner, Matthijs S Berends, Karsten Becker, Jutta Esser, Jens Gieffers, Annette Jurke, Greetje Kampinga, Stefanie Kampmeier, Rob Klont, Robin Köck, Lutz von Müller, Nashwan al Naemi, Alewijn Ott, Gijs Ruijs, Katja Saris, Adriana Tami, Andreas Voss, Karola Waar, Jan van Zeijl, Alex W Friedrich |
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| Přispěvatelé: | Microbes in Health and Disease (MHD) |
| Rok vydání: | 2022 |
| Předmět: |
Male
Methicillin-Resistant Staphylococcus aureus Cross Infection OUTCOMES ANTIMICROBIAL RESISTANCE Epidemiology Public Health Environmental and Occupational Health Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] Intensive Care Units All institutes and research themes of the Radboud University Medical Center lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Drug Resistance Multiple Bacterial Virology Humans Female Prospective Studies Delivery of Health Care Aged |
| Zdroj: | Euro Surveillance, 27, 5 Euro Surveillance, 27 Eurosurveillance, 27(5):2001660. EUR CENTRE DIS PREVENTION & CONTROL |
| ISSN: | 1025-496X 1560-7917 |
| Popis: | Background Antimicrobial resistance poses a risk for healthcare, both in the community and hospitals. The spread of multidrug-resistant organisms (MDROs) occurs mostly on a local and regional level, following movement of patients, but also occurs across national borders. Aim The aim of this observational study was to determine the prevalence of MDROs in a European cross-border region to understand differences and improve infection prevention based on real-time routine data and workflows. Methods Between September 2017 and June 2018, 23 hospitals in the Dutch (NL)–German (DE) cross-border region (BR) participated in the study. During 8 consecutive weeks, patients were screened upon admission to intensive care units (ICUs) for nasal carriage of meticillin-resistant Staphylococcus aureus (MRSA) and rectal carriage of vancomycin-resistant Enterococcus faecium/E. faecalis (VRE), third-generation cephalosporin-resistant Enterobacteriaceae (3GCRE) and carbapenem-resistant Enterobacteriaceae (CRE). All samples were processed in the associated laboratories. Results A total of 3,365 patients were screened (median age: 68 years (IQR: 57–77); male/female ratio: 59.7/40.3; NL-BR: n = 1,202; DE-BR: n = 2,163). Median screening compliance was 60.4% (NL-BR: 56.9%; DE-BR: 62.9%). MDRO prevalence was higher in DE-BR than in NL-BR, namely 1.7% vs 0.6% for MRSA (p = 0.006), 2.7% vs 0.1% for VRE (p Conclusions This first prospective multicentre screening study in a European cross-border region shows high heterogenicity in MDRO carriage prevalence in NL-BR and DE-BR ICUs. This indicates that the prevalence is probably influenced by the different healthcare structures. |
| Databáze: | OpenAIRE |
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