Nanozyme-Modified Metal–Organic Frameworks with Multienzymes Activity as Biomimetic Catalysts and Electrocatalytic Interfaces
| Autor: | Feng Gao, Caihua Qian, Pinghua Ling, Shan Cheng, Nuo Chen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Porphyrins
Materials science Biocompatibility Surface Properties Iron Metal Nanoparticles 02 engineering and technology 01 natural sciences Catalysis chemistry.chemical_compound Biomimetic Materials Nanotechnology Oxygen reduction reaction General Materials Science Porosity Metal-Organic Frameworks 010401 analytical chemistry Hydrogen Peroxide Catalase 021001 nanoscience & nanotechnology Porphyrin 0104 chemical sciences Kinetics Peroxidases chemistry Chemical engineering Metal-organic framework Zirconium Nanocarriers 0210 nano-technology Oxidation-Reduction Biosensor |
| Zdroj: | ACS Applied Materials & Interfaces. 12:17185-17192 |
| ISSN: | 1944-8252 1944-8244 |
| DOI: | 10.1021/acsami.9b23147 |
| Popis: | Many metal-organic frameworks have been designed and synthesized for biosensors because of high surface area and porosity, suitable size, and good biocompatibility. Despite recent advances, however, most of them are only used as a nanocarrier. In this work, a new artificial nanozyme was constructed on a metalloporphyrinic metal-organic framework (PMOF(Fe)), which was formed by Fe porphyrin and Zr4+ ions. Then, ultrasmall Pt nanoparticles (Pt NPs) were loaded on the surface of PMOF(Fe) to form Pt@PMOF(Fe). Because of the high surface area and exposed Fe activity center, PMOF(Fe) works as a nanocarrier to hinder the Pt NP aggregation and exhibits high peroxidase-mimicking activity. Hence, Pt NPs decorated on the surface of PMOF(Fe) possessed high stability and exhibited high activity. Due to the synergistic effect between PMOF(Fe) and Pt NPs, Pt@PMOF(Fe) exhibits superior catalase- and peroxidase-like activities. Moreover, Pt@PMOF(Fe) possesses high electrocatalytic activity toward the reduction of H2O2 and the oxygen reduction reaction (ORR). This strategy may serve as a strong foundation to design MOF-based artificial nanozymes and develop an ideal platform for MOFs and nanozymes toward artificial enzymatic catalytic systems, fuel cells and new analytical applications. |
| Databáze: | OpenAIRE |
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