Polymyxin Acute Kidney Injury: a case of severe tubulopathy
| Autor: | Thiago Florencio da Silva, Leticia Nicoletti Silva, Lucas Alexandre de Mello Goldin, Vinicius Daher Alvares Delfino |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.drug_class Polymyxin 030106 microbiology Hypokalemia Gastroenterology Nephrotoxicity Hypomagnesemia Kidney Tubules Proximal 03 medical and health sciences Electrolytes 0302 clinical medicine Tubulopathy Internal medicine medicine Humans Magnesium 030212 general & internal medicine Polymyxins Polymyxin B Hypocalcemia Toxicity business.industry Acute kidney injury Surgical wound General Medicine Acute Kidney Injury medicine.disease Diseases of the genitourinary system. Urology RC870-923 medicine.symptom business medicine.drug |
| Zdroj: | Brazilian Journal of Nephrology v.44 n.1 2022 Jornal Brasileiro de Nefrologia Sociedade Brasileira de Nefrologia (SBN) instacron:SBN Brazilian Journal of Nephrology n.ahead 2021 Brazilian Journal of Nephrology (2021) |
| Popis: | Polymyxins are antibiotics developed in the 1950s. Polymyxin-induced neurotoxicity has been often described in medical literature. The same cannot be said of nephrotoxicity or tubulopathy in particular. This report describes the case of a patient prescribed polymyxin B to treat a surgical wound infection, which led to significant increases in fractional excretion of calcium, magnesium, and potassium and subsequent persistent decreases in the levels of these ions, with serious consequences for the patient. Severe hypocalcemia, hypomagnesemia, and hypokalemia may occur during treatment with polymyxin. Calcium, magnesium and potassium serum levels must be monitored during treatment to prevent life-threatening conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|