Clinical implication of psoas muscle mass measurement for predicting death within 3 months in patients with incurable uterine cervical or corpus malignancy
| Autor: | Kaoru Minowa, Hiroyuki Kurosu, Yukiharu Todo, Tomohiko Tsuruta, Hidenori Kato, Ryutaro Yamada, Hiroko Matsumiya, Yoichi Mori, Shinichiro Minobe |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Cancer Research medicine.medical_specialty Uterine Cervical Neoplasms Malignancy Psoas Muscles Cachexia 03 medical and health sciences 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies Cancer Death Rate Receiver operating characteristic business.industry Area under the curve Cancer Organ Size General Medicine Middle Aged medicine.disease Confidence interval ROC Curve Oncology 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Radiology Tomography X-Ray Computed business |
| Zdroj: | Japanese Journal of Clinical Oncology. 51:577-583 |
| ISSN: | 1465-3621 |
| DOI: | 10.1093/jjco/hyaa248 |
| Popis: | Objective The aim of this study was to find a clinical marker for identifying refractory cancer cachexia. Methods We analyzed computed tomography imaging data, which included the third lumbar vertebra, from 94 patients who died of uterine cervix or corpus malignancy. The time between the date of examination and date of death was the most important attribute for this study, and the computed tomography images were classified into >3 months before death and ≤ 3 months before death. Psoas muscle mass index was defined as the left–right sum of the psoas muscle areas (cm2) at the level of third lumbar vertebra, divided by height squared (m2). Results A data set of 94 computed tomography images was obtained at baseline hospital visit, and a data set of 603 images was obtained at other times. One hundred (16.6%) of the 603 non-baseline images were scanned ≤3 months before death. Mean psoas muscle mass index change rates at >3 months before death and ≤3 months before death were −1.3 and −20.1%, respectively (P Conclusions Measuring change in psoas muscle mass index might be useful for predicting cancer mortality within 3 months. It could become a potential tool for identifying refractory cancer cachexia. |
| Databáze: | OpenAIRE |
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