Embryological outcomes in cycles with human oocytes containing large tubular smooth endoplasmic reticulum clusters after conventional in vitro fertilization
| Autor: | Fumiaki Itoi, Yukiko Asano, Masashi Shimizu, Yasutaka Murata, Hiroyuki Honnma |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult Endocrinology Diabetes and Metabolism medicine.medical_treatment Embryonic Development Fertilization in Vitro Biology Bioinformatics Andrology 03 medical and health sciences 0302 clinical medicine Endocrinology Human fertilization Pregnancy medicine Humans Blastocyst reproductive and urinary physiology Retrospective Studies 030219 obstetrics & reproductive medicine In vitro fertilisation urogenital system Endoplasmic reticulum Embryogenesis Obstetrics and Gynecology Endoplasmic Reticulum Smooth Oocyte 030104 developmental biology medicine.anatomical_structure Cytoplasm embryonic structures Oocytes Female Embryo quality |
| Zdroj: | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 32(4) |
| ISSN: | 1473-0766 |
| Popis: | There have been no studies analyzing the effect of large aggregates of tubular smooth endoplasmic reticulum (aSERT) after conventional in vitro fertilization (cIVF). The aim of this study was to investigate whether aSERT can be identified after cIVF and the association between the embryological outcomes of oocytes in cycles with aSERT. This is a retrospective study examining embryological data from cIVF cycles showing the presence of aSERT in oocytes 5-6 h after cIVF. To evaluate embryo quality, cIVF cycles with at least one aSERT-metaphase II (MII) oocyte observed (cycles with aSERT) were compared to cycles with normal-MII oocytes (control cycles). Among the 4098 MII oocytes observed in 579 cycles, aSERT was detected in 100 MII oocytes in 51 cycles (8.8%). The fertilization rate, the rate of embryo development on day 3 and day 5-6 did not significantly differ between cycles with aSERT and control group. However, aSERT-MII oocytes had lower rates for both blastocysts and good quality blastocysts (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|