Factors that influence outcomes in cochlear implantation in adults, based on patient related characteristics - a retrospective study

Autor: Véronique J. C. Kraaijenga, Wilko Grolman, Adriana L. Smit, Inge Stegeman, G.A. van Zanten, Jeanet J M Smilde
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Clinical Otolaryngology, 41(5), 585–592. Wiley-Blackwell
ISSN: 1749-4478
Popis: OBJECTIVE: Outcomes in speech perception following cochlear implantation in adults vary widely. Many studies have been carried out to identify and quantify factors that influence outcomes. This paper adds a new dimension to pre-existing literature. DESIGN: Single center retrospective cohort study. SETTING: University Medical Center Utrecht, The Netherlands. PARTICIPANTS: 428 adults with bilateral severe-to-profound sensorineural hearing loss, unilaterally implanted between February 1988 and March 2014. MAIN OUTCOME MEASURES: Univariable and multivariable linear regression analyses was carried out to identify factors that may influence outcomes from cochlear implantation. Consonant-vowel-consonant' word scores (CNCs) were recorded pre- and post-implant and were used as outcome measures in two groups of patients (pre- and postlingually deafened adults). As an added dimension, multiple imputation was implemented and evaluated to tackle 4% (17/407) missing data. RESULTS: For postlinguals, pre-implant speech perception score and age at onset of deafness are positive predictors and meningitis and otosclerosis as cause of deafness are negative predictors of post-implant speech perception. This model accounted for 26% of variance. For prelinguals, pre-implant speech perception score is the only strong positive predictor (Beta 0.524; p
Databáze: OpenAIRE