Nodal histiocytic disorder in children: report of three cases and review of literature
Autor: | Khadijah Mohd Nor, Indumathi Ainer, Salina Husain, H. S. Gendeh |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Tuberculosis Neck mass Lymphadenopathy Histopathology Langerhans cell Case report 03 medical and health sciences 0302 clinical medicine Langerhans cell histiocytosis Biopsy Medicine 030223 otorhinolaryngology Children Histiocyte medicine.diagnostic_test business.industry lcsh:Otorhinolaryngology medicine.disease lcsh:RF1-547 Lymphoma Histiocytosis 030220 oncology & carcinogenesis Lymph Radiology medicine.symptom business |
Zdroj: | The Egyptian Journal of Otolaryngology, Vol 36, Iss 1, Pp 1-5 (2020) |
ISSN: | 2090-8539 1012-5574 |
DOI: | 10.1186/s43163-020-00035-z |
Popis: | Background Histiocytic system consists of phagocytes and dendritic cells. Both are found in lymph nodes. Usually, this disorder presents with painless cervical lymph node enlargement hence frequently mistaken for lymphoma or tuberculosis. Case presentation Here, we report three pediatric cases: one of Langerhans cell histiocytosis and two of sinus histiocytosis and massive lymphadenopathy with neck mass as initial presentation. The final diagnosis was made with fine needle aspiration cytology, biopsy, and ancillary tests. Conclusion Biopsy and immunohistochemistry studies are recommended for determining subtypes of histiocytosis and further management of patient. |
Databáze: | OpenAIRE |
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