Low‐level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats

Autor: Luiz Gustavo de Sousa, Vitória Ricardo, Selma Siéssere, Lígia Maria Napolitano Gonçalves, Dimitrius Leonardo Pitol, Antônio Augusto Coppi, Marcelo Palinkas, Priscilla Hakime Scalize, Karina Fittipaldi Bombonato-Prado, Mariah Acioli Righeti, Simone Cecílio Hallak Regalo
Rok vydání: 2019
Předmět:
Zdroj: Animal Models and Experimental Medicine
ISSN: 2576-2095
DOI: 10.1002/ame2.12056
Popis: Background Osteoporosis can make bone repair difficult. Low‐level laser therapy (LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Methods Fifty‐four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups (n = 6 per group), and 24 hours after the bone defects were created they received 3, 6 or 12 sessions of LLLT at 0, 20 or 30 J/cm2, using a 780‐nm low‐intensity GaAlAs laser. One‐way ANOVA followed by Tukey's post hoc test was used for data processing. A difference of P
Databáze: OpenAIRE