Phenazinium Salt-Catalyzed Aerobic Oxidative Amidation of Aromatic Aldehydes
| Autor: | Dasheng Leow |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
Phenazine ethosulfate Aldehydes Molecular Structure Organic Chemistry Salt (chemistry) Oxidative phosphorylation Amides Biochemistry Catalysis chemistry.chemical_compound chemistry Photocatalysis Phenazines Organic chemistry Molecule Salts Organic synthesis Physical and Theoretical Chemistry Oxidation-Reduction Amide bonds |
| Zdroj: | Organic Letters. 16:5812-5815 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol5029354 |
| Popis: | Amides are prevalent in organic synthesis. Developing an efficient synthesis that avoids expensive oxidants and heating is highly desirable. Here the oxidative amidation of aromatic aldehydes is reported using an inexpensive metal-free visible light photocatalyst, phenazine ethosulfate, at low catalytic loading (1-2 mol %). The reaction proceeds at ambient temperature and uses air as the sole oxidant. The operationally easy procedure provides an economical, green, and mild alternative for the formation of amide bonds. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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