Selective Therapeutic Intervention: A Challenge against Off-Target Effects
| Autor: | Filip Rázga, Veronika Némethová |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Drug medicine.medical_specialty Drug discovery business.industry media_common.quotation_subject Selective intervention Pharmacology Off targets 03 medical and health sciences 030104 developmental biology Promiscuity Drug Design Intervention (counseling) medicine Animals Humans Molecular Medicine Intensive care medicine Adverse effect business Molecular Biology media_common |
| Zdroj: | Trends in Molecular Medicine. 23:671-674 |
| ISSN: | 1471-4914 |
| DOI: | 10.1016/j.molmed.2017.06.007 |
| Popis: | Despite the massive global spend on biology-driven drug discovery, tackling the issue of side effects and adverse events resulting from drug promiscuity represents a persistent challenge. Although delivering authentic medical innovations today is more complex than ever, minimization of off-target effects should be a priority. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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