Malignant melanoma: aetiological importance of individual pigmentation and sun exposure
| Autor: | Göran Wennersten, B. Mattson, H. Beitner, Ulrik Ringborg, S.E. Norell |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms genetic structures Population Skin Pigmentation Dermatology Black hair Risk Factors medicine Humans Risk factor Hair Color education Melanoma education.field_of_study Eye Color integumentary system biology Pigmentation business.industry biology.organism_classification medicine.disease Confidence interval Relative risk Sunlight Etiology Female business Sunscreening Agents Cabello |
| Zdroj: | British Journal of Dermatology. 122:43-51 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1990.tb08238.x |
| Popis: | SUMMARY A case-control study of cutaneous malignant melanoma (CMM) was based on 523 incident cases and 505 age- and sex-matched controls selected from the general population. The purpose was to investigate the relative risk of developing CMM associated with different sun habits and indicators of pigmentation, such as skin type, eye colour and hair colour. Compared to people with black hair, blonde subjects had a relative risk of 744 (95% confidence interval, 45.8–120.8). Associations with skin type and eye colour were considerably weaker. Relative risks of about 1.5–2.5 were found for certain sun habits. The results suggest that in a population of Caucasian origin with a predominantly fair complexion, pigmentary status characterized by hair colour is a far more important aetiological factor than sun habits. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text