Therapeutic effects of an alpha-casozepine and L-tryptophan supplemented diet on fear and anxiety in the cat
| Autor: | Bill Milgram, Christina de Rivera, Stephanie Kelly, Isabelle Mougeot, Gary M. Landsberg |
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| Rok vydání: | 2016 |
| Předmět: |
Male
040301 veterinary sciences medicine.drug_class Alpha (ethology) Physiology Anxiety Cat Diseases Anxiolytic 0403 veterinary science medicine Animals 0501 psychology and cognitive sciences 050102 behavioral science & comparative psychology Small Animals CATS Behavior Animal business.industry 05 social sciences Therapeutic effect Tryptophan Case-control study Caseins Original Articles Fear 04 agricultural and veterinary sciences Animal Feed Antidepressive Agents Peptide Fragments Diet Test (assessment) Case-Control Studies Dietary Supplements Test room Cats Female medicine.symptom business |
| Zdroj: | Journal of Feline Medicine and Surgery |
| ISSN: | 1532-2750 1098-612X |
| Popis: | Objectives This study assessed the anxiolytic effectiveness of a test diet (Royal Canin Feline Calm diet) supplemented with L-tryptophan and alpha-casozepine. Methods Subjects were 24 cats that were classified as mildly or markedly fearful based on the presence of a person in their home room. Three different protocols were used to assess anxiety: (1) evaluation of the response to a human in the cat’s home room (home room test); (2) analysis of the response to placement in an empty test room (open-field test); and (3) analysis of the response to an unfamiliar human (human interaction test). All three protocols were first run at baseline, and the results were used to assign the animals to control and test diet groups that showed equivalent fear and anxiety. Both groups were retested on the three protocols after 2 weeks (test 1) and again after 4 weeks (test 2). Results The diet groups differed for two behavioral measures in the open-field test: inactivity duration and inactivity frequency. The control group showed statistically significant increases in inactivity duration between baseline and test 1 and baseline and test 2, while the group fed the test diet showed a marginally not significant decrease in inactivity duration between baseline and test 1 and a not significant decrease for test 2. There was also a significant increase in inactivity frequency between baseline and test 1 in the test diet group and marginally not significant decrease in the control group. There were no differences between groups in the approach of the cats toward people for the home room test and the human interaction test. Conclusions and relevance These results suggest that the test diet reduced the anxiety response to placement in an unfamiliar location, but that fear in the presence of an unfamiliar person was not counteracted by the diet. |
| Databáze: | OpenAIRE |
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