Transcriptional abundance of antioxidant enzymes in endometrium and their circulating levels in Zebu cows with and without uterine infection

Autor: B.R. Maharana, R. K. Baithalu, Tushar Kumar Mohanty, T.K. Patbandha, Ashok Kumar Mohanty, N.M. Attupuram, Sudarshan Kumar, S.K. Agarwal, S. Kerketta, Arumugam Kumaresan, Sanjay Kumar Singh
Rok vydání: 2017
Předmět:
0301 basic medicine
medicine.medical_specialty
040301 veterinary sciences
Cattle Diseases
Ice calving
Biology
Nitric Oxide
Endometrium
Antioxidants
0403 veterinary science
Lipid peroxidation
03 medical and health sciences
chemistry.chemical_compound
Endocrinology
Food Animals
Pregnancy
Malondialdehyde
Internal medicine
Peripartum Period
medicine
Animals
RNA
Messenger
Pregnancy Complications
Infectious
Uterine Diseases
chemistry.chemical_classification
medicine.diagnostic_test
Glutathione peroxidase
Postpartum Period
Puerperal Disorders
04 agricultural and veterinary sciences
General Medicine
Enzymes
Oxidative Stress
030104 developmental biology
medicine.anatomical_structure
chemistry
Cattle
Female
Animal Science and Zoology
Lipid Peroxidation
Endometritis
Blood Chemical Analysis
Postpartum period
Endometrial biopsy
Zdroj: Animal Reproduction Science. 177:79-87
ISSN: 0378-4320
DOI: 10.1016/j.anireprosci.2016.12.008
Popis: Oxidative stress during peripartum period may compromise the uterine immunity. In the present study, we assessed the oxidative stress and antioxidant status during peripartum period and studied their relationship with postpartum uterine infection in dairy cows. Peripheral blood concentrations of total antioxidant capacity (TAC), malondialdehyde (MDA) and nitric oxide (NO) were determined (day -21, -7, on the day of calving and day +7, +21, +35) in normal (n=11), puerperal metritic (n=7) and clinical endometritic (n=6) cows. Endometrial biopsy was performed on the day of calving and expression of CAT, GPx4 and SOD2 genes was studied using qRT-PCR. Puerperal metritic cows had significantly (P
Databáze: OpenAIRE
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