Volume infusion cooling increases end-tidal carbon dioxide and results in faster and deeper cooling during intra-cardiopulmonary resuscitation hypothermia induction
| Autor: | Theodore Weiland, Lance B Becker, Robert A. Berg, Uday Illindala, George Bratinov, Joshua W Lampe |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Intra-ischemia hypothermia Cardiopulmonary resuscitation business.industry medicine.medical_treatment Research Technology choice Return of spontaneous circulation Targeted temperature management Hypothermia Critical Care and Intensive Care Medicine End tidal 3. Good health Surgery chemistry.chemical_compound chemistry Anesthesia Carbon dioxide Medicine Therapeutic hypothermia medicine.symptom business |
| Zdroj: | Intensive Care Medicine Experimental |
| ISSN: | 2197-425X |
| Popis: | Background Intra-arrest hypothermia induction may provide more benefit than inducing hypothermia after return of spontaneous circulation. However, little is understood about the interaction between patient physiology and hypothermia induction technology choice during ongoing chest compressions. Methods After 10 min of untreated ventricular fibrillation, mechanical chest compressions were provided for 60 min (100 CPM, 1.25" deep) in 26 domestic swine (30.5 ± 1.7 kg) with concurrent hypothermia induction using one of eight cooling methods. Four cooling methods included volume infusion with cold saline or an ice particulate slurry through the femoral vein or carotid artery (volume infusion cooling group, VC); three included cooling via an intra-vascular heat exchange catheter, nasal cooling, or surface ice bags (no volume cooling group, NVC); and the other was a control group with no cooling (no cooling group, NC). Physiological monitoring included end-tidal carbon dioxide, aortic pressure, right atrial pressure, brain temperature, esophageal temperature, and rectal temperature. Results During cardiopulmonary resuscitation (CPR), the volume infusion cooling group cooled faster and to lower temperatures than the other groups (VC vs. NVC or NC; ∆T = −5.6 vs. −2.1 °C or −0.6 °C; p |
| Databáze: | OpenAIRE |
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