Greater male than female variability in regional brain structure across the lifespan
| Autor: | Erick J. Canales-Rodríguez, Hans J. Grabe, Dirk J. Heslenfeld, Erik G. Jönsson, Oliver Gruber, Daniel Brandeis, Yang Wang, Henry Brodaty, Ruben C. Gur, Iris E. C. Sommer, Paul M. Thompson, Knut K. Kolskår, Christopher G. Davey, Dick J. Veltman, Eco J. C. de Geus, Tobias Banaschewski, Greig I. Zubicaray, Xavier Caseras, Sarah Baumeister, Raquel E. Gur, Vincent P. Clark, Maria J. Portella, Simon E. Fisher, Christopher R.K. Ching, Lars T. Westlye, Laura Koenders, Vince D. Calhoun, Carles Soriano-Mas, Nicholas G. Martin, Stefan Ehrlich, Fleur M. Howells, Catharina A. Hartman, Matthew D. Sacchet, Ole A. Andreassen, Josiane Bourque, Fabrice Crivello, Annette Conzelmann, Jaap Oosterlaan, Brenna C. McDonald, Gaelle E. Doucet, Avram J. Holmes, José M. Menchón, Danai Dima, Moji Aghajani, Joshua L. Roffman, Steven Williams, Lei Wang, David Mataix-Cols, Philip R. Szeszko, Bernd Weber, Tiril P. Gurholt, Sarah Hohmann, Ian H. Gotlib, Patricia Gruner, Anthony C. James, Paul Pauli, Lara M. Wierenga, Andrew M. McIntosh, Andrew J. Kalnin, Jim Lagopoulos, Henrik Walter, Andreas Reif, Andrew Simmons, Norbert Hosten, Pieter J. Hoekstra, Aristotle Voineskos, Alexander Tomyshev, Anton Albajes-Eizagirre, Jean-Paul Fouche, Dara M. Cannon, Ignacio Martínez‐Zalacaín, Geneviève Richard, Theophilus N. Akudjedu, David C. Glahn, Patricia J. Conrod, Ben J. Harrison, Alan Anticevic, Martine Hoogman, Francisco X. Castellanos, Bernd Kramer, Neda Jahanshad, Lieuwe de Haan, Dennis van der Meer, John D. West, Alan Breier, Jordan W. Smoller, P. G. P. Rosa, Katharina Wittfeld, Dan J. Stein, Jiyang Jiang, Jilly Naaijen, Christine Lochner, Dorret I. Boomsma, Alessandro Bertolino, Marise W. J. Machielsen, Hilleke E. Hulshoff Pol, Henry Völzke, Christian K. Tamnes, Ingrid Agartz, Georg C. Ziegler, Marieke Klein, Lars Nyberg, Perminder S. Sachdev, Philip Asherson, I.M. Veer, Sean N. Hatton, Núria Bargalló, Annabella Di Giorgio, Henk Temmingh, John A. Joska, Odile A. van den Heuvel, Wei Wen, Eveline A Crone, Kang Sim, Kathryn I. Alpert, Dennis van 't Ent, Jan K. Buitelaar, Joaquim Radua, Julian N. Trollor, B Mazoyer, Chaim Huyser, H. C. Whalley, Irina Lebedeva, Erin W. Dickie, Marcus Vinicus Zanetti, Stefan Borgwardt, Theodore D. Satterthwaite, Daniel H Wolf, Sophia I. Thomopoulos, Giulio Pergola, Luisa Lazaro, Ramona Baur-Streubel, Beathe Haatveit, Yannis Paloyelis, Ian B. Hickie, Jonna Kuntsi, Sophia Frangou, R. Salvador, Geraldo F. Busatto, Margaret J. Wright, Aurora Bonvino, Edith Pomarol-Clotet, Anouk den Braber, Lachlan T. Strike, Phil Lee, Anne Uhlmann, Yuliya N. Yoncheva, Mauricio H. Serpa, Dag Alnæs, Paola Fuentes-Claramonte, Katie L. McMahon, Andrew J. Saykin, Genevieve McPhilemy, Tiffany M. Chaim-Avancini, Sophie Maingault, Barbara Franke, Colm McDonald, Rachel M. Brouwer, Salvador Sarró |
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| Přispěvatelé: | Department of Psychology, Education and Child Studies, Biological Psychology, APH - Mental Health, APH - Methodology, Complex Trait Genetics, Amsterdam Neuroscience - Complex Trait Genetics, AMS - Ageing & Vitality, AMS - Sports, APH - Personalized Medicine, Cognitive Psychology, Clinical Neuropsychology, IBBA, Karolinska Schizophrenia Project (KaSP) Consortium, Adult Psychiatry, ANS - Complex Trait Genetics, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, Child Psychiatry, ANS - Cellular & Molecular Mechanisms, ANS - Amsterdam Neuroscience, General Paediatrics, ARD - Amsterdam Reproduction and Development, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Clinical Cognitive Neuropsychiatry Research Program (CCNP), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Movement Disorder (MD), Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health, Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Neurology, Amsterdam Neuroscience - Neurodegeneration, Anatomy and neurosciences, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, Pediatric surgery, Amsterdam Neuroscience - Brain Imaging |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
Netherlands Twin Register (NTR) SEGMENTATION Vulnerability Disease HM 0302 clinical medicine Anàlisi de variància 130 000 Cognitive Neurology & Memory diagnostic imaging [Cerebral Cortex] sexual characteristics Analysis of variance nuclear magnetic resonance imaging Cervell Research Articles Cerebral Cortex Sex Characteristics Radiological and Ultrasound Technology 05 social sciences Brain clinical trial Brain Structure Magnetic Resonance Imaging Early life Adolescence medicine.anatomical_structure Neurology Cerebral cortex Healthy individuals X-CHROMOSOME anatomy & histology [Cerebral Cortex] Evolution of the brain Female Anatomy Neurovetenskaper Research Article Radiology Nuclear Medicine and Medical Imaging Neuroinformatics SEX-DIFFERENCES diagnostic imaging brain Human Development BF Neuroimaging SURFACE-AREA Evolució del cervell Regional area Biology MULTISAMPLE 050105 experimental psychology brain cortex 03 medical and health sciences CEREBRAL-CORTEX Sex differences medicine Humans 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging human ddc:610 Cortical surface GENERAL INTELLIGENCE diagnostic imaging [Brain] METAANALYSIS biological variation HUMAN HIPPOCAMPUS Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7] physiology [Biological Variation Population] Neurosciences Gender Brain Cortical Thickness multicenter study Biological Variation Population Diferències entre sexes physiology RC0321 Radiologi och bildbehandling Neurology (clinical) anatomy & histology [Brain] 170 000 Motivational & Cognitive Control 030217 neurology & neurosurgery anatomy and histology meta analysis physiology [Human Development] Demography |
| Zdroj: | Human Brain Mapping. WILEY Human Brain Mapping Human Brain Mapping, 43, 1, pp. 470-499 Human Brain Mapping. Wiley-Liss Inc. Human Brain Mapping, 43(1), 470-499. Wiley-Liss Inc. Human Brain Mapping, 43, 470-499 Karolinska Schizophrenia Project (KaSP) consortium 2022, ' Greater male than female variability in regional brain structure across the lifespan ', Human Brain Mapping, vol. 43, no. 1, pp. 470-499 . https://doi.org/10.1002/hbm.25204, https://doi.org/10.1101/2020.02.17.952010 Human brain mapping 43(1), 470-499 (2022). doi:10.1002/hbm.25204 special issue: "The ENIGMA Consortium: the first 10 years" 2020, ' Greater male than female variability in regional brain structure across the lifespan ', Human Brain Mapping . https://doi.org/10.1002/hbm.25204 Human brain mapping, 43(1), 470-499. Wiley-Liss Inc. Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Human brain mapping, 43(1), 470-499. Wiley HUMAN BRAIN MAPPING r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname Human Brain Mapping, 43(1), 470-499. Wiley Karolinska Schizophrenia Project (KaSP) consortium 2022, ' Greater male than female variability in regional brain structure across the lifespan ', Human Brain Mapping, vol. 43, no. 1, pp. 470-499 . https://doi.org/10.1002/hbm.25204 |
| ISSN: | 1097-0193 1065-9471 |
| Popis: | Contains fulltext : 248376.pdf (Publisher’s version ) (Open Access) For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents the largest-ever mega-analysis of sex differences in variability of brain structure, based on international data spanning nine decades of life. Subcortical volumes, cortical surface area and cortical thickness were assessed in MRI data of 16,683 healthy individuals 1-90 years old (47% females). We observed significant patterns of greater male than female between-subject variance for all subcortical volumetric measures, all cortical surface area measures, and 60% of cortical thickness measures. This pattern was stable across the lifespan for 50% of the subcortical structures, 70% of the regional area measures, and nearly all regions for thickness. Our findings that these sex differences are present in childhood implicate early life genetic or gene-environment interaction mechanisms. The findings highlight the importance of individual differences within the sexes, that may underpin sex-specific vulnerability to disorders. |
| Databáze: | OpenAIRE |
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