Prognostic significance of major lipids in patients with acute ischemic stroke
Autor: | Konstantinos Tziomalos, Maria Tsopozidi, Apostolos I. Hatzitolios, Maria Papadopoulou, Marianna Spanou, Stavroula Kostaki, Stella-Maria Angelopoulou, Stella D. Bouziana, Christos Savopoulos, Vasilios Giampatzis |
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Rok vydání: | 2016 |
Předmět: |
Blood Glucose
Male medicine.medical_specialty 030204 cardiovascular system & hematology Biochemistry Brain Ischemia 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Predictive Value of Tests Modified Rankin Scale Internal medicine Heart rate medicine Humans Hospital Mortality Prospective Studies cardiovascular diseases Stroke Triglycerides Aged Aged 80 and over business.industry Cholesterol HDL Atrial fibrillation Cholesterol LDL Prognosis medicine.disease Lipids Confidence interval Blood pressure Relative risk Cardiology Physical therapy Female Neurology (clinical) business 030217 neurology & neurosurgery Dyslipidemia |
Zdroj: | Metabolic Brain Disease. 32:395-400 |
ISSN: | 1573-7365 0885-7490 |
Popis: | Although dyslipidemia increases the risk for ischemic stroke, previous studies reported conflicting data regarding the association between lipid levels and stroke severity and outcome. To evaluate the predictive value of major lipids in patients with acute ischemic stroke. We prospectively studied 790 consecutive patients who were admitted with acute ischemic stroke (41.0 % males, age 79.4 ± 6.8 years). The severity of stroke was assessed at admission with the National Institutes of Health Stroke Scale (NIHSS). Moderate/severe stroke was defined as NIHSS ≥5. The outcome was assessed with dependency rates at discharge (modified Rankin scale between 2 and 5) and with in-hospital mortality. Independent predictors of moderate/severe stroke were age (relative risk (RR) 1.05, 95 % confidence interval (CI) 1.02–1.08, p |
Databáze: | OpenAIRE |
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