Long-lasting Changes of Albino Rats Behavior and Brain Bioamines Content After Immunization Against Cholecystokinin-3 and -4
| Autor: | R. A. Danilova, Ludmila A. Andreeva, I. P. Ashmarin, O. I. Rudko, M. F. Obukhova |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Restraint Physical Long lasting Biogenic Amines medicine.medical_specialty Striatum Anxiety Active immunization digestive system Biochemistry Tetragastrin Cellular and Molecular Neuroscience Internal medicine medicine Animals CCK-4 Neurochemistry Rats Wistar Swimming Cholecystokinin business.industry digestive oral and skin physiology Brain General Medicine Corpus Striatum Rats Endocrinology Immunization business Oligopeptides Stress Psychological hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Neurochemical Research. 32:395-399 |
| ISSN: | 1573-6903 0364-3190 |
| Popis: | Active immunization against cholecystokinin fragments 31-33 (CCK-3) and 30-33 (CCK-4) results in long-lasting changes of albino rats' behavior. CCK-3 and CCK-4 covalently linked to antigen-carrier evokes the suppression of the anxiety, decreases some signs of depression-like behavior and changes the level of bioamines and their catabolites in striatum at least for two months after immunization. These data can provide a perspective approach to the problem of long term correction of behavior. |
| Databáze: | OpenAIRE |
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