CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation

Autor: Jun Kim, Jin Bae Kim, Jin-Kyu Park, Jeong Eun Yi, Jae Sun Uhm, Myung Jin Cha, Boyoung Joung, Tae Hoon Kim, Ki Woon Kang, Eue Keun Choi, Hyung Wook Park, Changsoo Kim, Young Soo Lee, Jaemin Shim, Junbeom Park, Jung Myung Lee
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Diagnostic Techniques
Cardiovascular
lcsh:Medicine
030204 cardiovascular system & hematology
Metabolic equivalent
0302 clinical medicine
Risk Factors
Atrial Fibrillation
030212 general & internal medicine
Prospective Studies
Young adult
Prospective cohort study
lcsh:Science
Multidisciplinary
Exercise Tolerance
Age Factors
Atrial fibrillation
Middle Aged
Prognosis
Stroke
Cardiorespiratory Fitness
Ischemic Attack
Transient
Research Design
Predictive value of tests
Hypertension
medicine.symptom
Adult
medicine.medical_specialty
Exercise intolerance
Asymptomatic
Risk Assessment
Article
03 medical and health sciences
Young Adult
Sex Factors
Predictive Value of Tests
Internal medicine
medicine
Humans
Vascular Diseases
Aged
Heart Failure
business.industry
lcsh:R
medicine.disease
Diabetes Mellitus
Type 2
CHA2DS2–VASc score
Asymptomatic Diseases
lcsh:Q
business
Zdroj: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
ISSN: 2045-2322
Popis: Exercise intolerance among the clinical symptoms in patients with atrial fibrillation (AF) has usually been masked by their adjusted life style. We sought to assess the role of CHA2DS2-VASc score to predict exercise intolerance in asymptomatic AF patients, and further examine whether the relationship differs by age and gender. Among the 6,275 participants of the prospective Korean registry of the Comparison study of Drugs for symptom control and complication prevention of Atrial Fibrillation (CODE-AF), 1,080 AF patients who underwent exercise treadmill testing were studied. Exercise intolerance was defined as a peak exercise capacity of 7 metabolic equivalents (METs) or less, and the patients were divided into two groups for the analysis: ≤7 METs (n = 131) and >7 METs (n = 949). Patients with exercise intolerance had a significantly higher CHA2DS2-VASc score than those without (3.1 ± 1.3 vs. 2.0 ± 1.5, p 2DS2-VASc score (OR 1.54, 95% CI 1.31–1.81, p 2DS2-VASc score on exercise intolerance was significant only in male patients aged 2DS2-VASc score may be a feasible risk assessment tool to predict exercise intolerance, especially in young and middle-aged male patients with asymptomatic AF.
Databáze: OpenAIRE
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