CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation
Autor: | Jun Kim, Jin Bae Kim, Jin-Kyu Park, Jeong Eun Yi, Jae Sun Uhm, Myung Jin Cha, Boyoung Joung, Tae Hoon Kim, Ki Woon Kang, Eue Keun Choi, Hyung Wook Park, Changsoo Kim, Young Soo Lee, Jaemin Shim, Junbeom Park, Jung Myung Lee |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Male
Diagnostic Techniques Cardiovascular lcsh:Medicine 030204 cardiovascular system & hematology Metabolic equivalent 0302 clinical medicine Risk Factors Atrial Fibrillation 030212 general & internal medicine Prospective Studies Young adult Prospective cohort study lcsh:Science Multidisciplinary Exercise Tolerance Age Factors Atrial fibrillation Middle Aged Prognosis Stroke Cardiorespiratory Fitness Ischemic Attack Transient Research Design Predictive value of tests Hypertension medicine.symptom Adult medicine.medical_specialty Exercise intolerance Asymptomatic Risk Assessment Article 03 medical and health sciences Young Adult Sex Factors Predictive Value of Tests Internal medicine medicine Humans Vascular Diseases Aged Heart Failure business.industry lcsh:R medicine.disease Diabetes Mellitus Type 2 CHA2DS2–VASc score Asymptomatic Diseases lcsh:Q business |
Zdroj: | Scientific Reports Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018) |
ISSN: | 2045-2322 |
Popis: | Exercise intolerance among the clinical symptoms in patients with atrial fibrillation (AF) has usually been masked by their adjusted life style. We sought to assess the role of CHA2DS2-VASc score to predict exercise intolerance in asymptomatic AF patients, and further examine whether the relationship differs by age and gender. Among the 6,275 participants of the prospective Korean registry of the Comparison study of Drugs for symptom control and complication prevention of Atrial Fibrillation (CODE-AF), 1,080 AF patients who underwent exercise treadmill testing were studied. Exercise intolerance was defined as a peak exercise capacity of 7 metabolic equivalents (METs) or less, and the patients were divided into two groups for the analysis: ≤7 METs (n = 131) and >7 METs (n = 949). Patients with exercise intolerance had a significantly higher CHA2DS2-VASc score than those without (3.1 ± 1.3 vs. 2.0 ± 1.5, p 2DS2-VASc score (OR 1.54, 95% CI 1.31–1.81, p 2DS2-VASc score on exercise intolerance was significant only in male patients aged 2DS2-VASc score may be a feasible risk assessment tool to predict exercise intolerance, especially in young and middle-aged male patients with asymptomatic AF. |
Databáze: | OpenAIRE |
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