Engineering polypeptide folding through trans double bonds: transformation of miniature β-meanders to hybrid helices

Autor:	Sushil N. Benke, K. Muruga Poopathi Raja, Mothukuri Ganesh Kumar, Hosahudya N. Gopi
Rok vydání:	2015
Předmět:	Protein Folding Double bond Stereochemistry Single step Peptide Conjugated system Crystallography X-Ray Protein Structure Secondary Catalysis Isomerism Materials Chemistry Amino Acid Sequence Catalytic hydrogenation chemistry.chemical_classification Metals and Alloys General Chemistry Surfaces Coatings and Films Electronic Optical and Magnetic Materials Folding (chemistry) Crystallography Transformation (genetics) chemistry Ceramics and Composites Hydrogenation Peptides Single crystal
Zdroj:	Chemical Communications. 51:13397-13399
ISSN:	1364-548X 1359-7345
DOI:	10.1039/c5cc04523a
Popis:	Utilization of conjugated double bonds to engineer the novel folded miniature β-meander type structures, single step transformation of miniature β-meanders into ααγ(4)-hybrid peptide 10/12-helices using catalytic hydrogenation, their solution and single crystal conformations are reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cf42ee9b400a46223b2865bab56ce3 https://doi.org/10.1039/c5cc04523a Zobrazit plný text záznamu