Quercetin Supplementation Improves Neuromuscular Function Recovery from Muscle Damage
| Autor: | Stefania Sabatini, Roberta Ceci, Guglielmo Duranti, Paolo Sgrò, Massimo Sacchetti, Ilenia Bazzucchi, Luigi Di Luigi, Federica Patrizio |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Weakness medicine.medical_specialty electromyography DOMS lcsh:TX341-641 Isometric exercise Electromyography Nerve conduction velocity Antioxidants Article 03 medical and health sciences Young Adult 0302 clinical medicine muscle damage Double-Blind Method Internal medicine Isometric Contraction medicine Eccentric Humans Muscle Strength elbow flexors Muscle Skeletal muscle weakness Nutrition and Dietetics Cross-Over Studies biology medicine.diagnostic_test business.industry Muscle weakness 030229 sport sciences Recovery of Function Crossover study Endocrinology Dietary Supplements biology.protein Creatine kinase Quercetin medicine.symptom business lcsh:Nutrition. Foods and food supply 030217 neurology & neurosurgery Food Science |
| Zdroj: | Nutrients Nutrients, Vol 12, Iss 2850, p 2850 (2020) Volume 12 Issue 9 |
| ISSN: | 2072-6643 |
| Popis: | This study was aimed at investigating whether quercetin (Q) may improve the recovery of neuromuscular function and biochemical parameters in the 7 days following an eccentric exercise-induced muscle damage (EEIMD). Sixteen men (25.9 ± 3.3 y) ingested Q (1000 mg/day) or placebo (PLA) for 14 days following a double-blind crossover study design. A neuromuscular (NM) test was performed pre&ndash post, 24 h, 48 h, 72 h, 96 h and 7 days after an intense eccentric exercise. The force&ndash velocity relationship of the elbow flexor muscles and their maximal voluntary isometric contraction (MVIC) were recorded simultaneously to the electromyographic signals (EMG). Pain, joint angle, arm circumference, plasma creatine kinase (CK) and lactate-dehydrogenase (LDH) were also assessed. The results showed that Q supplementation significantly attenuated the strength loss compared to PLA. During the recovery, force&ndash velocity relationship and mean fibers conduction velocity (MFCV) persisted significantly less when participants consumed PLA rather than Q, especially at the highest angular velocities (p < 0.02). A greater increase in biomarkers of damage was also evident in PLA with respect to Q. Q supplementation for 14 days seems able to ameliorate the recovery of eccentric exercise-induced weakness, neuromuscular function impairment and biochemical parameters increase probably due to its strong anti-inflammatory and antioxidant action. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|