The prognostic value of peak arterial lactate levels within 72 h of lung transplantation in identifying patient outcome
| Autor: | Guilong Wang, Shengjie Yuan, Qin Zhong, Jingjing Xu, Dongxiao Huang, Yanjuan Wang, Zhiping Wang, Jingyu Chen, Zhengfeng Gu, Chunxiao Hu |
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| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Proportional hazards model business.industry Mortality rate medicine.medical_treatment Hazard ratio Odds ratio Logistic regression medicine.disease Gastroenterology Internal medicine Lactic acidosis medicine Lung transplantation Original Article Hyperlactatemia business |
| Zdroj: | J Thorac Dis |
| ISSN: | 2072-1439 |
| Popis: | BACKGROUND: Lactic acidosis is often seen in lung transplantation (LTx). Postoperative lactate is frequently associated with poor outcome in postoperative and critically ill patients. Our aim was to evaluate the predictive value of postoperative peak lactate levels within 72 h of LTx for 30-day and late mortality. METHODS: We evaluated patients who underwent LTx from January 2015 to September 2017. All admitted patients were classified according to the peak lactate level (PL) within 72 h of surgery: PL 10 mmol/L (Group 3). We performed logistic regression analysis and used Cox regression models to identify the peak lactate level as a predictive factor for 30-day and late mortality, respectively. RESULTS: Of 255 eligible patients, mean age 55.61±12.16, mean lactate 4.99±2.93 and 80% male, and 40% had hyperlactatemia (PL >5 mmol/L) after LTx. The 30-day mortality rate was 17.9%, 28.9% and 68.8% in the three groups, respectively (P |
| Databáze: | OpenAIRE |
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