Endobronchial ultrasound transbronchial biopsy with guide-sheath for the diagnosis of solitary pulmonary nodules
| Autor: | Qi Yuan, Chunhua Xu, Wei Wang, Yong Lin, Like Yu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
solitary pulmonary nodules Benign disease medicine.diagnostic_test business.industry Malignancy medicine.disease transbronchial biopsy Respiratory Medicine endobronchial ultrasound 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Oncology Pneumothorax Biopsy medicine 030212 general & internal medicine Radiology Endobronchial ultrasound Transbronchial biopsy business guide-sheath Research Paper Procedure time |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| DOI: | 10.18632/oncotarget.16813 |
| Popis: | // Chun-Hua Xu 1, 2, * , Qi Yuan 1, 2, * , Li-Ke Yu 1, 2 , Wei Wang 1, 2 and Yong Lin 3 1 Endoscopic Center of Nanjing Chest Hospital, Nanjing, Jiangsu 210029, China 2 Clinical Center of Nanjing Respiratory Diseases and Imaging, Nanjing, Jiangsu 210029, China 3 Department of Respiratory Medicine, Nanjing Chest Hospital, Nanjing, Jiangsu 210029, China * These authors have contributed equally to this work Correspondence to: Chun-Hua Xu, email: xuchunhua_nj@163.com Keywords: endobronchial ultrasound, transbronchial biopsy, guide-sheath, solitary pulmonary nodules Received: December 08, 2016 Accepted: March 16, 2017 Published: April 04, 2017 ABSTRACT The aim of this study was to assess the usefulness of endobronchial ultrasound transbronchial biopsy with guide-sheath (EBUS-GS-TBB) for the diagnosis of solitary pulmonary nodules (SPNs). One hundred and eighty patients, who were diagnosed with SPNs and underwent an endobronchial ultrasound procedure. The diagnostic yield, safety and the associated factors were analyzed. Mean EBUS-GS procedure time was 14±8 min. The average number of biopsy specimens obtained in each SPNs was 5±1.2. One hundred and thirty-four SPNs were diagnosed by EBUS-GS-TBB and the diagnostic rate was 74.4 %. The diagnosis rate of malignancy was 83.3 %, while that of benign disease was 56.7 %. The most important factors that helped enhance EBUS-GS diagnostic accuracy included lesion diameter greater than 20mm, EBUS probe within the lesions and central lesions. No pneumothorax, hemoptysis or other serious complications occurred with the diagnostic procedures. EBUS-GS-TBB is a safe and effective method for diagnosing SPNs. |
| Databáze: | OpenAIRE |
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