Virtual 2D angiography from four-dimensional digital subtraction angiography (4D-DSA): A feasibility study
| Autor: | Rajkamal Khangura, Kerstin Mueller, Jay F. Yu, Robert Darflinger, Steven W. Hetts, Hataka Minami, Leland Pung, Daniel L Cooke |
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| Rok vydání: | 2020 |
| Předmět: |
Intracranial Arteriovenous Malformations
Intracerebral hemorrhage medicine.medical_specialty medicine.diagnostic_test business.industry Angiography Subtraction Angiography Digital Subtraction Digital subtraction angiography Gold standard (test) medicine.disease 030218 nuclear medicine & medical imaging body regions 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Dose area product medicine Feasibility Studies Humans Radiology business 030217 neurology & neurosurgery Cerebrovascular pathology |
| Zdroj: | Interv Neuroradiol |
| ISSN: | 2385-2011 1591-0199 |
| DOI: | 10.1177/1591019920961604 |
| Popis: | Background Digital subtraction angiography (DSA) remains the gold standard for angiographic evaluation of cerebrovascular pathology, however, multiple acquisitions requiring additional time and radiation are often needed. In contrast, 3D-DSA provides volumetric information from a single injection but neglects temporal information. Four-dimensional-DSA (4D-DSA) combines temporal information of 2D-DSA with volumetric information of 3D-DSA to provide time-resolved tomographic 3D reconstructions, potentially reducing procedure time and radiation. This work evaluates the diagnostic quality of virtual single-frame 4D-DSA relative to 2D-DSA images by assessing clinicians’ ability to evaluate cerebrovascular pathology. Methods Single-frame images of four projections from 4D-DSA and their corresponding 2D-DSA images (n = 15) were rated by two neurointerventional radiologists. Images were graded based on diagnostic quality (0 = non-diagnostic, 1 = poor, 2 = acceptable, 3 = good). Dose area product (DAP) for each case was recorded for all 2D-DSA, 4D-DSA acquisitions, and the overall procedure. Results The mean diagnostic quality of all four 4D-DSA projections from both raters was 1.75 while the mean of 2D-DSA projections was 2.8. Student’s t-test revealed significant difference in diagnostic quality between 4D-DSA and 2D-DSA at all four projections (p Conclusions The difference in image quality between virtual single-frame 4D-DSA and their respective 2D-DSA images is statistically significant. Furthermore, 4D-DSA acquisitions require less radiation dose than conventional procedures with 2D-DSA acquisitions. |
| Databáze: | OpenAIRE |
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