Results from a retrospective analysis of colonoscopies for Inflammatory bowel disease and colorectal cancer in a Lebanese tertiary care centre
| Autor: | Toufic Saber, Khalil Bedran, Roula Bou Khalil, Mansour El Khoury, Fatima Ghandour, Said Farhat |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Colorectal cancer Colon Population Colonoscopy Inflammatory bowel disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine education Original Research education.field_of_study adenocarcinoma medicine.diagnostic_test business.industry Incidence (epidemiology) ibd Cancer medicine.disease Ulcerative colitis digestive system diseases 030220 oncology & carcinogenesis Adenocarcinoma 030211 gastroenterology & hepatology business colonic diseases |
| Zdroj: | BMJ Open Gastroenterology |
| ISSN: | 2054-4774 |
| Popis: | Background and aims Inflammatory bowel diseases (IBDs) and colorectal cancer have an increased impact on the Lebanese population’s morbidity and mortality. This study evaluated the situation of IBD and colorectal cancer at a tertiary hospital centre in Lebanon. Methods 1007 patients underwent colonoscopy over a period of 12 months by qualified physicians. 91 patients were excluded from the study. Biopsy results were divided into normal versus abnormal colonic tissue. The abnormal section was further subdivided into number of polyps, IBD, dysplasia and cancer. Results Out of 916 individuals included, 61 cases of Crohn’s colitis (CC) (6.7%) and 24 cases of ulcerative colitis (UC) (2.7%) were identified. A total of 92 cases of colorectal cancer (10.04%) were also identified. There was a slight male predominance in both groups of IBD without any statistical significance. One statistical significance was reported in favour to age50 years and male gender significantly correlate with an increased incidence of precancerous and cancerous polyps in the colon. They significantly correlate with adenocarcinoma. The estimated incidence of colorectal cancer, CC and UC was 54.1, 35.8 and 14.1 per 100 000, respectively, with a denominator of 169 959 patients per year. Conclusion Within the limitations of this study, the incidence of colorectal cancer and IBD falls in the high range compared with similar European and American studies. Our data are biased because of the tertiary centre setting but they can be considered as base for further investigations. |
| Databáze: | OpenAIRE |
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