Hypothyroidism and urinary incontinence:Prevalence and association in a Danish, female sample from the Lolland-Falster Health study
| Autor: | Peter Gæde, Lisbeth Bonde, Jennie Laigaard, Lars Alling Møller, Helga Gimbel, Ea Løwenstein, Lea Laird Andersen, Randi Jepsen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Pediatrics endocrine system endocrine system diseases Epidemiology Denmark Population Urinary incontinence Physical examination Hypothyroidism Risk Factors Subclinical hypothyroidism Diabetes mellitus Surveys and Questionnaires medicine Prevalence Humans education Subclinical infection Lolland-Falster Health Study (LOFUS) education.field_of_study medicine.diagnostic_test business.industry Obstetrics and Gynecology Odds ratio medicine.disease Cross-Sectional Studies Urinary Incontinence Reproductive Medicine Female medicine.symptom business Body mass index hormones hormone substitutes and hormone antagonists |
| Zdroj: | Løwenstein, E, Jepsen, R, Andersen, L L, Laigaard, J, Møller, L A, Gæde, P, Bonde, L & Gimbel, H 2021, ' Hypothyroidism and urinary incontinence : Prevalence and association in a Danish, female sample from the Lolland-Falster Health study ', European Journal of Obstetrics and Gynecology and Reproductive Biology, vol. 264, pp. 232-240 . https://doi.org/10.1016/j.ejogrb.2021.07.020 |
| Popis: | Introduction We aimed to estimate the prevalence of urinary incontinence (UI) in women with hypothyroidism and subclinical hypothyroidism and to examine the association of hypothyroidism and UI. Methods This cross-sectional study was based on the population-based Lolland-Falster Health Study (LOFUS), Denmark. Data comprising a questionnaire, physical examination, and blood samples were collected between 2016 and 2020. Multiple logistic regression was used to estimate odds ratios (OR) and control for possible confounders: age, body mass index, diabetes, smoking, and education. Results Of 7,699 women included in the study, 7.9% had hypothyroidism, and 2.4% had subclinical hypothyroidism. The prevalence of any UI in women with hypothyroidism, subclinical hypothyroidism, and a control group (normal level of thyroid hormones) was 43.6%, 38.1%, and 39.3%, respectively. After controlling for confounders, no association between hypothyroidism and any UI (OR 1.01, 95% CI 0.85-1.20) or frequent UI (OR 1.05, 95% CI 0.84-1.32) were demonstrated. Additional, no association between subclinical hypothyroidism and any UI (OR 0.87, 95% CI 0.64-1.18) or frequent UI (OR 1.15, 95 CI 0.79-1.69) were demonstrated. Conclusions In our female sample, the prevalence of UI was high regardless of the thyroid status. No association between hypothyroidism and any or frequent UI was demonstrated. The prevalence of hypothyroidism was 7.9%. |
| Databáze: | OpenAIRE |
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